CRISPR

CRISPR1-magoh

ID

ZDB-CRISPR-210208-2

Name

CRISPR1-magoh

Previous Names

None

Target

magoh (1)

Sequence

5' - GGTACTATGTGGGGCATAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
oz37	magoh

Expression

Gene expression in Wild Types + CRISPR1-magoh

No data available

Phenotype

Phenotype resulting from CRISPR1-magoh

No data available

Phenotype of all Fish created by or utilizing CRISPR1-magoh

Phenotype	Fish	Conditions	Figures
muscle cell disorganized, abnormal	magoh^oz37/oz37	standard conditions	Fig 3 from Gangras et al., 2020
motor neuron axon decreased length, abnormal	magoh^oz37/oz37	standard conditions	Fig 3 , Fig 8 from Gangras et al., 2020
myotome U-shaped, abnormal	magoh^oz37/oz37	standard conditions	Fig 3 from Gangras et al., 2020
trunk curved ventral, abnormal	magoh^oz37/oz37	standard conditions	Fig 2 , text only from Gangras et al., 2020
whole organism atxn1b expression increased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 5 from Gangras et al., 2020
whole organism gtpbp1l expression increased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 5 from Gangras et al., 2020
whole organism eif4a3 expression decreased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 2 from Gangras et al., 2020
whole organism gadd45aa expression increased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 5 from Gangras et al., 2020
head necrotic, abnormal	magoh^oz37/oz37	standard conditions	Fig 2 from Gangras et al., 2020
whole organism dead, abnormal	magoh^oz37/oz37	standard conditions	text only from Gangras et al., 2020
whole organism paralysed, abnormal	magoh^oz37/oz37	standard conditions	Fig 3 from Gangras et al., 2020
muscle contraction decreased occurrence, abnormal	magoh^oz37/oz37	standard conditions	Fig 3 from Gangras et al., 2020
whole organism neuromuscular junction decreased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 3 from Gangras et al., 2020
whole organism necrotic, abnormal	magoh^oz37/oz37	standard conditions	text only from Gangras et al., 2020
whole organism magoh expression decreased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 2 , Fig 8 from Gangras et al., 2020
heart edematous, abnormal	magoh^oz37/oz37	standard conditions	text only from Gangras et al., 2020
whole organism rbm8a expression decreased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 2 , Fig 8 from Gangras et al., 2020
whole organism foxo3b expression increased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 8 from Gangras et al., 2020
whole organism eif4a2 expression increased amount, abnormal	magoh^oz37/oz37	standard conditions	Fig 5 from Gangras et al., 2020
motor neuron axon decreased length, abnormal	magoh^oz37/oz37; foxo3b^ihb404/+	standard conditions	Fig 8 from Gangras et al., 2020
motor neuron axon decreased length, ameliorated	magoh^oz37/oz37; foxo3b^{ihb404/ihb404}	standard conditions	Fig 8 from Gangras et al., 2020

Citations