CRISPR

CRISPR1-rab28

ID

ZDB-CRISPR-201022-1

Name

CRISPR1-rab28

Previous Names

None

Target

rab28 (1)

Sequence

5' - CAAGAGAATCACACTGCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

View all 26 target locations

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ucd7	rab28
ucd8	rab28

Expression

Gene expression in Wild Types + CRISPR1-rab28

No data available

Phenotype

Phenotype resulting from CRISPR1-rab28

No data available

Phenotype of all Fish created by or utilizing CRISPR1-rab28

Phenotype	Fish	Conditions	Figures
eye all-trans-retinyl palmitate decreased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 8 from Moran et al., 2022
response to light stimulus disrupted, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	FIGURE 2 from Carter et al., 2020
eye 11-cis-retinyl palmitate decreased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 8 from Moran et al., 2022
eye retinoid decreased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 8 from Moran et al., 2022
retinal pigmented epithelium phagocytic vesicle decreased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	FIGURE 3 from Carter et al., 2020
eye N-retinylidene-N-retinylphosphatidylethanolamine increased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 8 from Moran et al., 2022
retina phagocytic vesicle opn1sw1 expression decreased distribution, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	FIGURE 3 from Carter et al., 2020
eye park7 expression increased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 7 from Moran et al., 2022
eye rab7a expression decreased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 7 from Moran et al., 2022
eye calr expression increased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 7 from Moran et al., 2022
eye 11-cis-retinal decreased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 8 from Moran et al., 2022
eye dnm1l expression increased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 7 from Moran et al., 2022
optomotor response disrupted, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	FIGURE 2 from Carter et al., 2020
eye rp2 expression decreased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 7 from Moran et al., 2022
retinal pigmented epithelium autophagosome decreased amount, abnormal	rab28^ucd7/ucd7 (TU)	standard conditions	Fig. 3 , Fig. 4 from Moran et al., 2022
retinal pigmented epithelium phagocytic vesicle decreased amount, abnormal	rab28^ucd8/ucd8 (TU)	standard conditions	FIGURE 3 from Carter et al., 2020
response to light stimulus disrupted, abnormal	rab28^ucd8/ucd8 (TU)	standard conditions	FIGURE 2 from Carter et al., 2020
retina phagocytic vesicle opn1sw1 expression decreased distribution, abnormal	rab28^ucd8/ucd8 (TU)	standard conditions	FIGURE 3 from Carter et al., 2020
optomotor response disrupted, abnormal	rab28^ucd8/ucd8 (TU)	standard conditions	FIGURE 2 from Carter et al., 2020
retinal pigmented epithelium autophagosome amount, ameliorated	rab28^ucd7/ucd7; ucd10Tg (TU)	standard conditions	Fig. 4 from Moran et al., 2022
retinal pigmented epithelium autophagosome amount, ameliorated	rab28^ucd7/ucd7; ucd11Tg (TU)	standard conditions	Fig. 4 from Moran et al., 2022
retinal pigmented epithelium autophagosome amount, ameliorated	rab28^ucd7/ucd7; ucd12Tg (TU)	standard conditions	Fig. 4 from Moran et al., 2022

Citations