CRISPR

CRISPR12-kmt2d

ID
ZDB-CRISPR-200515-2
Name
CRISPR12-kmt2d
Previous Names
None
Target
Sequence
5' - GTATTGACTGTGGCATGCGA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 23
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zy58 kmt2d
zy59 kmt2d
zy60 kmt2d
1 - 3 of 3
Expression
Gene expression in Wild Types + CRISPR12-kmt2d
No data available
Phenotype
Phenotype resulting from CRISPR12-kmt2d
Phenotype Fish Figures
atrium notch1b expression spatial pattern, abnormal um14Tg + CRISPR12-kmt2d Fig 6 with image from Serrano et al., 2019
cardiac ventricle notch1b expression increased distribution, abnormal um14Tg + CRISPR12-kmt2d Fig 6 with image from Serrano et al., 2019
1 - 2 of 2
Phenotype of all Fish created by or utilizing CRISPR12-kmt2d
Phenotype Fish Conditions Figures
head decreased size, abnormal kmt2dzy58/zy58 (AB) standard conditions Fig 1 with image from Serrano et al., 2019
pericardium edematous, abnormal kmt2dzy58/zy58 (AB) standard conditions Fig 1 with image from Serrano et al., 2019
whole organism anterior-posterior axis decreased length, abnormal kmt2dzy58/zy58 (AB) standard conditions Fig 1 with image from Serrano et al., 2019
ethmoid cartilage morphology, abnormal kmt2dzy59/zy59 (AB) standard conditions Fig 2 with image from Serrano et al., 2019
head decreased size, abnormal kmt2dzy59/zy59 (AB) standard conditions Fig 1 with image,  Fig 2 with image from Serrano et al., 2019
1 - 5 of 66 Show all
Citations
TSV
1 - 1 of 1
Show
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.