CRISPR

CRISPR1-kl

ID

ZDB-CRISPR-200415-3

Name

CRISPR1-kl

Previous Names

None

Target

kl (1)

Sequence

5' - GGCTGGAGTAATTCGGTTATGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3212	kl
zf3213	kl

Expression

Gene expression in Wild Types + CRISPR1-kl

No data available

Phenotype

Phenotype resulting from CRISPR1-kl

No data available

Phenotype of all Fish created by or utilizing CRISPR1-kl

Phenotype	Fish	Conditions	Figures
eye protruding, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 1 from Singh et al., 2019
heart mmp13a expression increased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 4 from Singh et al., 2019
whole organism viability, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 1 from Singh et al., 2019
epidermis necrotic, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
whole organism calcified, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
dermis vasculature mineralized, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
kidney kl expression decreased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 3 from Singh et al., 2019
whole organism inflammatory response increased occurrence, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
bone tissue located in pharyngeal arch 3-7, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
eye opaque, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 1 from Singh et al., 2019
fin broken, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 1 from Singh et al., 2019
swimming decreased occurrence, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 1 from Singh et al., 2019
bulbus arteriosus osteoclast increased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
bulbus arteriosus calcified, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
heart entpd5a expression increased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 4 from Singh et al., 2019
common bile duct calcified, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
skeletal muscle vasculature mineralized, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
heart ctsk expression increased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 4 from Singh et al., 2019
heart mmp9 expression increased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 4 from Singh et al., 2019
skeletal muscle degenerate, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
skeletal muscle fibrotic, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
heart spp1 expression increased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 4 from Singh et al., 2019
gill fgf23 expression increased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 3 from Singh et al., 2019
heart acp5a expression increased amount, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 4 from Singh et al., 2019
bulbus arteriosus spp1 expression mislocalised, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 4 from Singh et al., 2019
dermis necrotic, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 2 from Singh et al., 2019
whole organism decreased weight, abnormal	kl^{zf3212/zf3212} (TU)	standard conditions	Fig. 1 from Singh et al., 2019
eye protruding, abnormal	kl^{zf3213/zf3213} (AB)	standard conditions	Fig. 1 from Singh et al., 2019
whole organism viability, abnormal	kl^{zf3213/zf3213} (AB)	standard conditions	Fig. 1 from Singh et al., 2019
fin broken, abnormal	kl^{zf3213/zf3213} (AB)	standard conditions	Fig. 1 from Singh et al., 2019
swimming decreased occurrence, abnormal	kl^{zf3213/zf3213} (AB)	standard conditions	Fig. 1 from Singh et al., 2019
eye opaque, abnormal	kl^{zf3213/zf3213} (AB)	standard conditions	Fig. 1 from Singh et al., 2019
whole organism decreased weight, abnormal	kl^{zf3213/zf3213} (AB)	standard conditions	Fig. 1 from Singh et al., 2019

Citations