CRISPR

CRISPR1-klf4

ID

ZDB-CRISPR-190925-1

Name

CRISPR1-klf4

Previous Names

None

Target

Sequence

5' - GGCGCTCCTGGCCAAGGAAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genome Build: GRCz11Chromosome: 21

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
as32	klf4

Expression

Gene expression in Wild Types + CRISPR1-klf4

No data available

Phenotype

Phenotype resulting from CRISPR1-klf4

No data available

Phenotype of all Fish created by or utilizing CRISPR1-klf4

Phenotype	Fish	Conditions	Figures
keratinocyte decreased amount, abnormal	klf4^as32/as32	standard conditions	Fig 2 from Chen et al., 2019
epidermis somatic stem cell decreased amount, abnormal	klf4^as32/as32	standard conditions	Fig 2 from Chen et al., 2019
ionocyte decreased amount, abnormal	klf4^as32/as32	standard conditions	Fig 2 , Fig. S2 from Chen et al., 2019
keratinocyte decreased amount, abnormal	klf4^as32/+	standard conditions	Fig 2 from Chen et al., 2019
epidermis somatic stem cell decreased amount, abnormal	klf4^as32/+	standard conditions	Fig 2 , Fig. S6 from Chen et al., 2019
epidermis somatic stem cell amount, ameliorated	klf4^as32/+ + MO1-cdkn1a	standard conditions	Fig. S6 from Chen et al., 2019
epidermis somatic stem cell amount, ameliorated	klf4^as32/+ + MO4-tp53	standard conditions	Fig. S6 from Chen et al., 2019

Citations

Include unpublished citations

1 - 1 of 1

Show