CRISPR

CRISPR9-tp53

ID

ZDB-CRISPR-190919-7

Name

CRISPR9-tp53

Previous Names

None

Target

Sequence

5' - AGTATTCAGCCCCCAGGTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ka801	tp53

Expression

Gene expression in Wild Types + CRISPR9-tp53

No data available

Phenotype

Phenotype resulting from CRISPR9-tp53

No data available

Phenotype of all Fish created by or utilizing CRISPR9-tp53

Phenotype	Fish	Conditions	Figures
swimming behavior decreased duration, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 6 from Elabd et al., 2019
swimming behavior decreased occurrence, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 6 from Elabd et al., 2019
hatching delayed, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 3 from Elabd et al., 2019
whole organism viability, ameliorated	tp53^ka801/ka801 (AB)	radiation	Fig. 2 from Elabd et al., 2019
developmental growth decreased rate, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 3 from Elabd et al., 2019
whole organism viability, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 3 from Elabd et al., 2019
whole organism tp63 expression increased amount, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 5 from Elabd et al., 2019
whole organism tp73 expression increased amount, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 5 from Elabd et al., 2019
somitogenesis increased duration, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 3 from Elabd et al., 2019
thigmotaxis latency, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 6 from Elabd et al., 2019
whole organism pou5f3 expression increased amount, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 4 from Elabd et al., 2019
thigmotaxis decreased duration, abnormal	tp53^ka801/ka801 (AB)	standard conditions	Fig. 6 from Elabd et al., 2019

Citations