CRISPR

CRISPR2-sox1b

ID

ZDB-CRISPR-190718-9

Name

CRISPR2-sox1b

Previous Names

None

Target

Sequence

5' - GGAGTGGAAACTCATGTCCG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genome Build: GRCz11Chromosome: 1

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ka702	sox1b

Expression

Gene expression in Wild Types + CRISPR2-sox1b

No data available

Phenotype

Phenotype resulting from CRISPR2-sox1b

No data available

Phenotype of all Fish created by or utilizing CRISPR2-sox1b

Phenotype	Fish	Conditions	Figures
spinal cord gata3 expression increased distribution, abnormal	sox1a^ka701/ka701; sox1b^ka702/ka702	standard conditions	Fig. 6 from Gerber et al., 2019
VeLD increased amount, abnormal	sox1a^ka701/ka701; sox1b^ka702/ka702	standard conditions	Fig. 6 from Gerber et al., 2019
spinal cord tal2 expression increased distribution, abnormal	sox1a^ka701/ka701; sox1b^ka702/ka702	standard conditions	Fig. 6 from Gerber et al., 2019
spinal cord tal1 expression increased distribution, abnormal	sox1a^ka701/ka701; sox1b^ka702/ka702	standard conditions	Fig. 6 from Gerber et al., 2019
spinal cord gata2a expression increased distribution, abnormal	sox1a^ka701/ka701; sox1b^ka702/ka702	standard conditions	Fig. 6 from Gerber et al., 2019
locomotion decreased occurrence, abnormal	sox1a^ka701/ka701; sox1b^ka702/ka702	standard conditions	Fig. 7 from Gerber et al., 2019

Citations

Include unpublished citations

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