CRISPR

CRISPR10-kmt2d

ID
ZDB-CRISPR-181017-3
Name
CRISPR10-kmt2d
Previous Names
None
Target
Sequence
5' - GGGTGAGGTGCTGATAAACGTGG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM site was TGG at the 3' end.
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 23
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
rdu1001 kmt2d
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Expression
Gene expression in Wild Types + CRISPR10-kmt2d
No data available
Phenotype
Phenotype resulting from CRISPR10-kmt2d
Phenotype Fish Figures
convergent extension involved in gastrulation disrupted, abnormal EKW + CRISPR10-kmt2d Fig. S7 with image from Tsai et al., 2018
mandibular arch skeleton morphology, abnormal EKW + CRISPR10-kmt2d Fig. S7 with image from Tsai et al., 2018
Meckel's cartilage decreased distance ceratohyal cartilage, abnormal EKW + CRISPR10-kmt2d Fig. S7 with image from Tsai et al., 2018
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Phenotype of all Fish created by or utilizing CRISPR10-kmt2d
Phenotype Fish Conditions Figures
brain cell population proliferation process quality, ameliorated kmt2drdu1001/rdu1001 chemical treatment by environment: B-Raf inhibitor Fig. 6 with image from Tsai et al., 2018
convergent extension involved in gastrulation process quality, ameliorated kmt2drdu1001/rdu1001 chemical treatment by environment: B-Raf inhibitor Fig. 6 with image from Tsai et al., 2018
Meckel's cartilage decreased distance ceratohyal cartilage, abnormal kmt2drdu1001/rdu1001 standard conditions Fig. 6 with image from Tsai et al., 2018
mandibular arch skeleton morphology, abnormal kmt2drdu1001/rdu1001 standard conditions Fig. 6 with image from Tsai et al., 2018
mandibular arch skeleton morphology, ameliorated kmt2drdu1001/rdu1001 chemical treatment by environment: B-Raf inhibitor Fig. 6 with image from Tsai et al., 2018
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Citations
TSV
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