CRISPR

CRISPR1-gmfb

ID

ZDB-CRISPR-180924-1

Name

CRISPR1-gmfb

Previous Names

None

Target

gmfb (1)

Sequence

5' - GATTGACAAAGACAAACAGCTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf2158	gmfb

Expression

Gene expression in Wild Types + CRISPR1-gmfb

No data available

Phenotype

Phenotype resulting from CRISPR1-gmfb

No data available

Phenotype of all Fish created by or utilizing CRISPR1-gmfb

Phenotype	Fish	Conditions	Figures
microglial cell glial cell projection decreased size, abnormal	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 6 from Yin et al., 2018
telencephalon cxcl8a expression amount, ameliorated	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 6 from Yin et al., 2018
telencephalon gmfb expression absent, abnormal	gmfb^{zf2158/zf2158}	control	Fig. 2 from Yin et al., 2018
radial glial cell glial filament decreased size, abnormal	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 4, Fig. 5 from Yin et al., 2018
whole organism gmfb expression absent, abnormal	gmfb^{zf2158/zf2158}	control	Fig. 2 from Yin et al., 2018
telencephalon radial glial cell decreased amount, abnormal	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 3 from Yin et al., 2018
telencephalon il1b expression amount, ameliorated	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 6 from Yin et al., 2018
radial glial cell glial filament disorganized, abnormal	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 4 from Yin et al., 2018
head gmfb expression absent, abnormal	gmfb^{zf2158/zf2158}	control	Fig. 2 from Yin et al., 2018
microglial cell response to wounding process quality, abnormal	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 6 from Yin et al., 2018
telencephalon tnfa expression amount, ameliorated	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 6 from Yin et al., 2018
radial glial cell cell population proliferation decreased occurrence, abnormal	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 3 from Yin et al., 2018
telencephalon inflammatory response to wounding decreased occurrence, abnormal	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 6 from Yin et al., 2018
radial glial cell response to wounding process quality, abnormal	gmfb^{zf2158/zf2158}	surgical manipulation: telencephalon	Fig. 3, Fig. 5 from Yin et al., 2018

Citations