CRISPR

CRISPR1-aanat2

ID

ZDB-CRISPR-170830-2

Name

CRISPR1-aanat2

Previous Names

None

Target

Sequence

5' - GGCAAAGACGACACACGTTAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
sus013	aanat2

Expression

Gene expression in Wild Types + CRISPR1-aanat2

No data available

Phenotype

Phenotype resulting from CRISPR1-aanat2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-aanat2

Phenotype	Fish	Conditions	Figures
whole organism cxcl8b.1 expression decreased amount, abnormal	aanat2^{sus013/sus013}	transection: caudal fin	Fig. 6 from Ren et al., 2017
whole organism clocka expression decreased amount, abnormal	aanat2^{sus013/sus013}	standard conditions	Fig. 4 from Ren et al., 2017
whole organism per1b expression decreased amount, abnormal	aanat2^{sus013/sus013}	standard conditions	Fig. 4 from Ren et al., 2017
whole organism bmal1b expression decreased amount, abnormal	aanat2^{sus013/sus013}	standard conditions	Fig. 4 from Ren et al., 2017
whole organism bmal1a expression decreased amount, abnormal	aanat2^{sus013/sus013}	standard conditions	Fig. 4 from Ren et al., 2017
whole organism per2 expression increased amount, abnormal	aanat2^{sus013/sus013}	standard conditions	Fig. 4 from Ren et al., 2017
whole organism il1b expression decreased amount, abnormal	aanat2^{sus013/sus013}	transection: caudal fin	Fig. 6 from Ren et al., 2017
neutrophil chemotaxis disrupted, abnormal	aanat2^{sus013/sus013}; nz117Tg	transection: caudal fin	Fig. 3 from Ren et al., 2017
whole organism neutrophil migration disrupted, abnormal	aanat2^{sus013/sus013}; nz117Tg	transection: caudal fin	Fig. 3 from Ren et al., 2017
whole organism melatonin decreased amount, abnormal	aanat2^{sus013/sus013}; nz117Tg	standard conditions	Fig. 2 from Ren et al., 2017

Citations