CRISPR

CRISPR1-edn3b

ID

ZDB-CRISPR-170328-1

Name

CRISPR1-edn3b

Previous Names

None

Target

Sequence

5' - GGATAAATGTACTCACTGTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
b1283	edn3b
mk203	edn3b

Expression

Gene expression in Wild Types + CRISPR1-edn3b

No data available

Phenotype

Phenotype resulting from CRISPR1-edn3b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-edn3b

Phenotype	Fish	Conditions	Figures
whole organism decreased life span, ameliorated	edn3b^mk203/mk203 (AB)	cancer xenotransplantation	Fig. 4 from Kim et al., 2017
whole organism melanoma increased amount, ameliorated	edn3b^mk203/mk203 (AB)	cancer xenotransplantation	Fig. 4 from Kim et al., 2017
melanocyte decreased pigmentation, abnormal	edn3b^mk203/mk203 (AB)	standard conditions	Fig. 4 from Kim et al., 2017
melanocyte decreased amount, abnormal	edn3b^mk203/mk203 (AB)	standard conditions	Fig. 4 from Kim et al., 2017
melanocyte shape, abnormal	edn3b^mk203/mk203 (AB)	standard conditions	Fig. 4 from Kim et al., 2017
whole organism neoplasm increased amount, abnormal	edn3b^mk203/mk203 (AB)	cancer xenotransplantation	Fig. 4 from Kim et al., 2017
hypodermal cell melanocyte decreased amount, abnormal	edn3a^b1282/b1282; edn3b^b1283/b1283 (AB/TU)	standard conditions	Fig. 3 from Spiewak et al., 2018
hypodermal cell iridophore decreased amount, abnormal	edn3a^b1282/b1282; edn3b^b1283/b1283 (AB/TU)	standard conditions	Fig. 3 from Spiewak et al., 2018
peritoneum iridophore absent, abnormal	edn3a^b1282/b1282; edn3b^b1283/b1283 (AB/TU)	standard conditions	Fig. 3 from Spiewak et al., 2018

Citations