CRISPR

CRISPR2-lepa

ID

ZDB-CRISPR-160816-4

Name

CRISPR2-lepa

Previous Names

None

Target

lepa (1)

Sequence

5' - GGAATCTCTGGATAATGTCCTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
nz301	lepa

Expression

Gene expression in Wild Types + CRISPR2-lepa

No data available

Phenotype

Phenotype resulting from CRISPR2-lepa

Phenotype	Fish	Figures
pancreas has extra parts of type pancreatic B cell, abnormal	vu513Tg + CRISPR2-lepa	Fig. 3 from Michel et al., 2016

Phenotype of all Fish created by or utilizing CRISPR2-lepa

Phenotype	Fish	Conditions	Figures
blood glucose increased amount, abnormal	lepa^nz301/nz301 (AB)	chemical treatment by environment: glucose	Fig. 1 from Kamstra et al., 2022
glucose homeostasis process quality, ameliorated	lepa^nz301/nz301 (AB)	chemical treatment by environment: lithium chloride	Fig. 4 from Kamstra et al., 2022
glucose homeostasis process quality, ameliorated	lepa^nz301/nz301 (AB)	chemical treatment by injection: Leptin, chemical treatment by environment: lithium chloride	Fig. 4 from Kamstra et al., 2022
blood glucose increased amount, abnormal	lepa^nz301/nz301 (AB)	nutrient increased	Fig. 2 from Kamstra et al., 2022
blood glucose amount, ameliorated	lepa^nz301/nz301 (AB)	chemical treatment by injection: Leptin, chemical treatment by environment: glucose	Fig. 1 from Kamstra et al., 2022
glucose homeostasis process quality, ameliorated	lepa^nz301/nz301 (AB)	chemical treatment by injection: Leptin	Fig. 4 from Kamstra et al., 2022
glucose homeostasis decreased process quality, abnormal	lepa^nz301/nz301 (AB)	chemical treatment by environment: glucose	Fig. 1 from Kamstra et al., 2022
glucose homeostasis process quality, ameliorated	lepa^nz301/nz301 (AB)	chemical treatment by injection: Leptin, chemical treatment by environment: glucose	Fig. 1 from Kamstra et al., 2022
whole organism increased mass, abnormal	lepa^nz301/nz301 (AB)	nutrient increased	Fig. 2 from Kamstra et al., 2022
glucose homeostasis decreased process quality, abnormal	lepa^nz301/nz301 (AB)	control	Fig. 4 from Kamstra et al., 2022
whole organism increased length, abnormal	lepa^nz301/nz301 (AB)	nutrient increased	Fig. 2 from Kamstra et al., 2022
pancreas has extra parts of type pancreatic B cell, abnormal	vu513Tg + CRISPR2-lepa	standard conditions	Fig. 3 from Michel et al., 2016

Citations