Genomic Feature
m780
- ID
- ZDB-ALT-980203-446
- Name
- m780
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Driever Lab
- Current Source
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The m610 and m780 alleles are likely re-isolates of the same mutational event. ... | Holzschuh et al., 2003 |
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 24: 8723081 (GRCz11) (1) Details
- Nucleotide change
- T/C
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- A>G (1)
- Transcript Consequence
- Cryptic Acceptor Splice Site, Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
GGCAGATCTGTACTCCTTTCATTGGCACACTGCTTTACTGATTTAGAGAAGTGCATTGTCCGCAAATCCCAGAATTAACTGTGTGTTTTATTAATTAAAAAAAAACTAAATGCCAAGATCGGAAGGTGGTGGGTTCAGTGTTTCATCTTGATCACTAGTGTGTTTGTTATATGTAGTTTGTCATATTAGTTGGGAGGTGGTGGTTGGATATCACTTTCTGTGCTTCTCATCTTTGTCACCCGCTTTCGACCCCGTCTCACTGTGGCTGTTGGGATTGTTGTTCAGGTACATTTTGTCCATTGCTTTAATTGCCTCCGTCAGATAGTTCTGCAGAGCTGTGAGGGCCGCACAGACGGCCGGAGTTCCGAATCCGTGAGAAATAAGACTGAAGTGGGTCAAACAGCTCTGAATCCCGGGCTCGAGAATGGGTTGTGGACGTGAATTCCCCAAGGGCGAGCGGTCTTGAGACAGCAGGTCCGTGAACTCTTTGCAGATTTGTC
T/C AGAAGGAGACACAATGCAGGATGCGTGTCAGGAGGAAGCTAATTACAGCTGATGCTATGACGTCATACATGTATTAGTAAGACTATGTGGTCCATATGTGTCCTTTAATCGATGACACACGTATTCCGTTTGACAGTAGCTGGATGGGCAGTGTCGTGTCATAGCGATGGACAATTCACGTTCAGCTTAAGAGAGCCGCATCTATGTCAGAAACGGATGAGGGAGTCGTCTTGTATGTTTTTATTCTAAATCGTTGTTGTTTGCAGTCTTATGTGTTTTAATTGACACTGGTGCTGATCTTTTTTATTTAAACTTTTTTTTTTTTTATTGCATCAAATATGCCGATATATTTCATTGCAGAAAGCATACCGTTTCGTGGAATATTTGAAATATACTTCATAAAACCAAACGGCTCCAAAAAGCAGGAATTAAACCAGCTCTGTTTATTAAAATCTAAATGTAACAAATTTTTAGTACACGTATAGGCGATCCAGCATAAG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| tfap2am780/m780 (AB) | Homozygous | Unknown | 2 figures  from 2 publications |
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Supplemental Information
- Genotyping protocol
- None
- Holzschuh, J., Barrallo Gimeno, A., Ettl, A.K., Durr, K., Knapik, E.W., and Driever, W. (2003) Noradrenergic neurons in the zebrafish hindbrain are induced by retinoic acid and require tfap2a for expression of the neurotransmitter phenotype. Development (Cambridge, England). 130(23):5741-5754
- Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J., and Boggs, C. (1996) A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123:37-46
- Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Abdelilah, S., Stainier, D.Y., and Driever, W. (1996) Mutations affecting craniofacial development in zebrafish. Development (Cambridge, England). 123:357-367
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