Genomic Feature
m456
- ID
- ZDB-ALT-980203-430
- Name
- m456
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Driever Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 2: 37203343 (GRCz11) (1) Details
- Nucleotide change
- G/T
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- G>T in Donor Splice Site (1)
- Transcript Consequence
- Cryptic Acceptor Splice Site, Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
CCTATATCCTGCAGTTGCTGCTGTTGCACTTCTGGTTAGACCTAATTTGCATTTTGTTGTCTTGTACTTTTACATGTGTAATAACAAAGTTGAATCTAATCTAAAACAAAATGGAATTTTAATTTTAAATTGAATTTTTTCCTGATCGTTCCACTGCTTAGAACTTGCATTGAGCGGTGCAGTATGTACAAGTTGAAATCCTTTTAACTTGACACTGCTTTTTAAAACACAGCACATGTGTTAGGCACTGCTAAAGATGCTAGACACAAGCATAATGGTCGAGCTCATTTACATAGAAAAACTATGGAAAAGTAGCATATTAGAATGGACCAAATGCATTGTGAATGAACTGTAACCTTCAAAATAAACCCTACTTTACTGTCACTCAGGCCCAGCAGCTGATCACTATTTGTAAGGAGTATATTATTGGCCTCACGATGGAGACGGAGAGGAAGAAACTCCCTAAAGACAGTCTTGATGAGCAGAAGAGAATTTGTGAG
G/T TATGTGCTTTAGATAATCATCTGAAATATGCTGCACCTTATGGACCAAGTTAATATTTAGATCTCTTCTGTGTGTTTCAGATGGCGGCGTATTTCACACACTGCAGTCTTCAGCCTGTCCACATGGTGTTGGTTTTGAGAACGGCACTCAATCTTTTCTTCAAACTGCGCAACTTTAAAACTGCAGCAGGTTTTGCTCGCCGTCTGCTTGAGCTAGGCCCCAAACCTGAAGTGGCACAGCAGGTGAATTAATGGTTGTTTTGTTTTTTAGGACAGTGTAATGCAGGGTTGTCCAAGCTCGGTCCTCGAAAGCCAGTGTCCTGCATAGTTTAGCTTGAAACTTCTAGACAGGCGTGTTGAAAAGTTCTAATATACCTGCCTGGTTCAGGTGTGTTTTATTAGGGTTGGAACTAGGCATGGGATGATGACTGTTTTCAGCGGTTTGGAAAAGCAGAAGCCAATGATTCATTTGAATTATTCAGCCTGACATGTTTACTGCTC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| copam456/m456 (AB) | Homozygous | ♀+/- ♂+/- | 7 figures  from 3 publications | 4 figures from 2 publications | |
| copam456/+ (AB) | Heterozygous | Unknown |
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Supplemental Information
- Genotyping protocol
- None
- Coutinho, P., Parsons, M.J., Thomas, K.A., Hirst, E.M., Saude, L., Campos, I., Williams, P.H., Stemple, D.L. (2004) Differential Requirements for COPI Transport during Vertebrate Early Development. Developmental Cell. 7(4):547-558
- Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J., and Boggs, C. (1996) A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123:37-46
- Haffter, P., Granato, M., Brand, M., Mullins, M.C., Hammerschmidt, M., Kane, D.A., Odenthal, J., van Eeden, F.J., Jiang, Y.J., Heisenberg, C.P., Kelsh, R.N., Furutani-Seiki, M., Vogelsang, E., Beuchle, D., Schach, U., Fabian, C., and Nüsslein-Volhard, C. (1996) The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development (Cambridge, England). 123:1-36
- Stemple, D.L., Solnica-Krezel, L., Zwartkruis, F., Neuhauss, S.C., Schier, A.F., Malicki, J., Stainier, D.Y., Abdelilah, S., Rangini, Z., Mountcastle-Shah, E., and Driever, W. (1996) Mutations affecting development of the notochord in zebrafish. Development (Cambridge, England). 123:117-128
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