Genomic Feature
tz310b
- ID
- ZDB-ALT-980203-1778
- Name
- tz310b
- Synonyms
-
- AZ110B (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Nüsslein-Volhard Lab
- Current Source
- European Zebrafish Resource Center (EZRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 7: 28586756 (GRCz11) (1) Details
- Nucleotide change
- T/A
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- None
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation: Lys>Stop (1)
- Flanking Sequence
-
TAAAATGCCATTCAAACTCACACTATTTAACACTGAATAAAGCACGTAAGGTGTACCTGAAGTAATTATAGTTCATCCTGTTGTTCACCTGTAAAAAATAGAAGCCGTTTCTAAAATAGAAATTTCAGGATTTTTAGGACAAAAAATACTTTTAATGAGGCAAACTATTTTTTTTACCGCATGTCATTGCTTTTATTTAGAAAGGCCTGGTTTCAGCCTTATTTCAGGCTTGACAGACACACTCTTGTTGATGTCGTCAATCTGGCAACCTGCTCCTGCATGTGTTTTCAACCAGGAGTACAATACCTAGTTCAACCATTGGGTGTCAAACTTACATGTTGCACCCTTCAATAATCTTCTTCTTAATGAACTTGATGAACAAATTTGAAACTACAGCTGTCAATTAATTAAAATGAAGAACAATTTTGTAAAGAAAGACCTGTTGCAACAGCACTAACTACTATAAGCATATATTTTCACAATGGACTCACCACATTTTT
T/A ATCCAGCAGAATTTGTCCAGTGCCGCAATGATCTGGTGTGTCAGCGGGTCGGACGAGTTTCTTAGCCAGTTCATACTCTGATCCAGCAAAGTGTAGATGAAACTGCTCTCGGTTAATGGACTTGCGAAGAGTACGGATGGTCTTCCTAAGCCGCTTCTCAGAGCGCCGCCGAACACAAGTCAGGTCACAGCCCTCTGCTGAGAGAAACAATAGATACCATATTTCATCCACAACAGCATCATAATAAATGCACACAACGTTCATGCTGTCTACAATGCCCACTTCCATCATAAACCAGGAGATACTTTCACCTGTTGGCTTGTTTTAGTCACAGCGACAGGAGCGGGAAGACGGTGAGATGCGAGCAAGCAAATGAGAAGGTTTATAGTGAAACGTACGCATGCGGTACACAAAACCAACCTGTTACCTCCTCCAGGTTCACATCCAGCTCAAACTGGGCAGTAATGAAGGAGCCTTCCTCCTCGCCAGCCTTCCGCCCG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| scube2tz310b/tz310b | Homozygous | Unknown | 2 figures from 2 publications | ||
| scube2tz310b/tz310b | Homozygous | ♀+/- ♂+/- | Table 1 from Chen et al., 1996 | ||
| scube2tz310b/tz310b + MO1-gdf6a | Complex |
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Supplemental Information
- Genotyping protocol
- None
- Kannan, R.R., Iniyan, A.M., Vincent, S.G. (2015) Chemical genetic effects of Sargassum wightii during embryonic development in zebrafish. Indian journal of pharmacology. 47:195-8
- Kawakami, A., Nojima, Y., Toyoda, A., Takahoko, M., Satoh, M., Tanaka, H., Wada, H., Masai, I., Terasaki, H., Sakaki, Y., Takeda, H., and Okamoto, H. (2005) The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling. Current biology : CB. 15(5):480-488
- Chen, J.N., Haffter, P., Odenthal, J., Vogelsang, E., Brand, M., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Kelsh, R.N., Mullins, M.C., and Nüsslein-Volhard, C. (1996) Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development (Cambridge, England). 123:293-302
- Haffter, P., Granato, M., Brand, M., Mullins, M.C., Hammerschmidt, M., Kane, D.A., Odenthal, J., van Eeden, F.J., Jiang, Y.J., Heisenberg, C.P., Kelsh, R.N., Furutani-Seiki, M., Vogelsang, E., Beuchle, D., Schach, U., Fabian, C., and Nüsslein-Volhard, C. (1996) The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development (Cambridge, England). 123:1-36
- van Eeden, F.J., Granato, M., Schach, U., Brand, M., Furutani-Seiki-, M., Haffter, P., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., Warga, R.M., Allende, M.L., Weinberg, E.S., and Nüsslein-Volhard, C. (1996) Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development (Cambridge, England). 123:153-164
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