Genomic Feature
tm94
- ID
- ZDB-ALT-980203-1100
- Name
- tm94
- Synonyms
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Nüsslein-Volhard Lab
- Current Source
- European Zebrafish Resource Center (EZRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 7: 53103463 (GRCz11) (1) Details
- Nucleotide change
- A/T
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- T>A (1)
- Transcript Consequence
- Missense (1)
- Protein Consequence
- Amino Acid Substitution: Val>Asp at position 162 (1)
- Flanking Sequence
-
TTTTCCAAAGCTTCAGGAACATTTCCATTAAAAGGGTTTTGAGTAAACACAGGCTTATTATCATTTTGGTCTGTCACAGTTACAATAATGTCCATTGGCTTTTCTGTGACATCCGCGTCCACTCCGTTTGCATGAGCCCTAAGCTAAAAACATAATAGGGGGATGACAGGACATACCCGAGATGTTTATTGCTATTTTTATACTCGTATATAACTATAATTACAACAATAATCTTATCAGCTTACTTTGTATGATGCTTTTTTTTCTCTGTCAAGTAGCTGAGTCACACTGACCCATCCTGATAGTCTGTCTATCGTGAAAATACCCTTAGGGTCTAGATCTGCCCCTTCACCAGTGATCTTGTATGCCAACCGAGTTTCAATAGCATAATCCGACTTTATCTAAATGCAGAGACCAATCAGAAAAACATTCAAAACAGACAAATCTTAATTTTCTGAATTTCATTTTAAATAGTTCATTCTTAACTGTTACTGACCTGG
A/T CCAGCCTCATTGGGAATGGACCTTTGCTATTTTCAGATACACTGATTGGAGGAATAATCCAACCTCTCTTTACTCTTTTATTTTTAGTCAGATCCACATCAGAGGAAGATTCCACCTAAGAACATAGTAAAAGGTCAAAGTGACGTAACACACCCAGACACACAGTAAAATTAACAATGACATATAGTGCATCGATTAAACAGGTTTAATTGTTGTTAGCTAAATAGTAGGTATGTAGCCTGGGTTTAAAAAAAAAGGAATAAAAAAAAAACTTGAACGGTTTTATACATGTTCGTATAAATGGAGAAATTACTCCTAGAATCAGAAACTCGGGTTTGAACATACGTAATGACAATCAATAATAAGGAGGACAGACACATACTTATACGTTCCAGACACAACATCTGGGAATGGAAAGCTTTTCTAAAAAGGAAACTTTGCTAGTCATGACAAAAACTCATTTTGATATGGAACTGTTTAGGACACAATGTATTCTAGCA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| cdh1tm94/tm94 | Homozygous | ♀+/- ♂+/- | 2 figures  from 2 publications |
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Supplemental Information
- Genotyping protocol
- None
- Warga, R.M., Kane, D.A. (2018) Probing Cadherin Interactions in Zebrafish with E- and N-Cadherin Missense Mutants. Genetics. 210(4):1391-1409
- Kane, D.A., McFarland, K.N., and Warga, R.M. (2005) Mutations in half baked/E-cadherin block cell behaviors that are necessary for teleost epiboly. Development (Cambridge, England). 132(5):1105-1116
- McFarland, K.N., Warga, R.M., and Kane, D.A. (2005) Genetic locus half baked is necessary for morphogenesis of the ectoderm. Developmental Dynamics : an official publication of the American Association of Anatomists. 233(2):390-406
- Haffter, P., Granato, M., Brand, M., Mullins, M.C., Hammerschmidt, M., Kane, D.A., Odenthal, J., van Eeden, F.J., Jiang, Y.J., Heisenberg, C.P., Kelsh, R.N., Furutani-Seiki, M., Vogelsang, E., Beuchle, D., Schach, U., Fabian, C., and Nüsslein-Volhard, C. (1996) The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development (Cambridge, England). 123:1-36
- Kane, D.A., Hammerschmidt, M., Mullins, M.C., Maischein, H.M., Brand, M., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Haffter, P., Heisenberg, C.P., Jiang, Y.J., Kelsh, R.N., Odenthal, J., Warga, R.M., and Nüsslein-Volhard, C. (1996) The zebrafish epiboly mutants. Development (Cambridge, England). 123:47-55
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