Genomic Feature
fds1
- ID
- ZDB-ALT-221117-9
- Name
- fds1
- Synonyms
-
- zf3528 (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- Lab of Origin
- Bertolucci Lab
- Current Source
- Other Pages
-
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 7: 31926405 - 31926448 (GRCz11) (1) Details
- Nucleotide change
- ACGGCAGCGGCAGCAGCGGCAGCGGCGCCCAGGTAGCCCTCGGC/GCCC
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 4 bp inserted / 44 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
ACCCCAAGGGGTTGCATTTGGTCTCGTAAAAGTATTGCTTCAGCTGACCATTAGTCACGGGGACCTTCTCCAGAACGGTGACCGTCTGGCCCGACATGTCTATTGCCGTCTTTTTGTCCACAGCTGTCACCCACTGGCTAATACTGTCACAAACGCTGAGCTCCCCCCGCCGTGCGGGGTCCGAGTGTCGCCGCACACGCATCGACATGTTGGCGGCATCCAGGTAGTTTTTGTATTCCTCCAAGAGAAAGAGTAACGGCGGCTCCAAAGGCACTTGGTTGCTGATCATCACCCGCGAGGCATACAGGTCAACGTCCTTCGAGTCTGCCGCATCTATAGGGCCGCCCCCTCCTTGGCCCTGGTCGGCCCCAGGCCCCAGTTGCTGCGTCGCTTCCCCTTCCACCTCAAGCAACTCCTCAATGACCTGCTCGAAAGTGTCCGTGAGCGAGGGCAGCCCGCCCCCACTCTGTGGAGTCCCGTGGCCTCGGCTGCCCGATGTG
ACGGCAGCGGCAGCAGCGGCAGCGGCGCCCAGGTAGCCCTCGGC/GCCC CCGGTGGCCCCCCTGCACGCCCGGGATCTCTCTCATGGGCGCAGCTCTCATGCAACTGAAGTATGAAATAACCATAGTAACGAACAGGATGGTCATCACTCTTCTAACCTGTTGGAACTGGAGACAGCAAAAGGGGAAGGACAAGAGGGATGGGGGAGTGAGGAAAAGGGGAGGGGGGGACAGAAAACAAAATGTAAAACAACTGTTTTGCAAACAACATTGCATTAAACACTTCATTCATAATAAAAAAAAAAGGTTCTTATAGTGGCGAATCATTCCCGTGGCGCAATTTGAAGCAAAACACAAACACAACGTGCCAACTTGTTATTTCTTTGTTTCATTTTTAGTCTCATGCCCATGGGAGCGCAACTAACACTCTGTCCCTGCACATACACCTGCACGTTTGTGCCCCCTCCCCTTTCCAACACCAGCAAATACAGCAGGCTAAATTCAGAGACCCTGGAGTATCATTAGGAGGACACAAGAGAACTGCTCCCACT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| bdnffds1/fds1 (AB) | Homozygous | ♀+/- ♂+/- | 4 figures  from D'Agostino et al., 2022 | 2 figures from D'Agostino et al., 2022 | |
| bdnffds1/+ (AB) | Heterozygous | ♀+/- ♂+/- | Fig. 2 from D'Agostino et al., 2022 |
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Supplemental Information
- Genotyping protocol
- None
- D'Agostino, Y., Frigato, E., Noviello, T.M.R., Toni, M., Frabetti, F., Cigliano, L., Ceccarelli, M., Sordino, P., Cerulo, L., Bertolucci, C., D'Aniello, S. (2022) Loss of circadian rhythmicity in bdnf knockout zebrafish larvae. iScience. 25:104054
- Lucon-Xiccato, T., Montalbano, G., Gatto, E., Frigato, E., D'Aniello, S., Bertolucci, C. (2022) Individual differences and knockout in zebrafish reveal similar cognitive effects of BDNF between teleosts and mammals. Proceedings. Biological sciences. 289:2022203620222036
- Lucon-Xiccato, T., Tomain, M., D'Aniello, S., Bertolucci, C. (2022) bdnf loss affects activity, sociability, and anxiety-like behaviour in zebrafish. Behavioural brain research. 436:114115
- Maffioli, E., Angiulli, E., Nonnis, S., Grassi Scalvini, F., Negri, A., Tedeschi, G., Arisi, I., Frabetti, F., D'Aniello, S., Alleva, E., Cioni, C., Toni, M. (2022) Brain Proteome and Behavioural Analysis in Wild Type, BDNF+/- and BDNF-/- Adult Zebrafish (Danio rerio) Exposed to Two Different Temperatures. International Journal of Molecular Sciences. 23(10)
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