Genomic Feature
zf3367
- ID
- ZDB-ALT-220208-4
- Name
- zf3367
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Venkatesh Lab
- Current Source
- Other Pages
-
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 10: 15122578 - 15122581 (GRCz11) (1) Details
- Nucleotide change
- ATCG/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 4 bp deleted in Exon 7 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
GGTCAGTTGAGATGGATTGACACTGTCCATTAAGTGAAGTTTAATTTTAAGGTATCTTATCTGATTCTTGGAAGAAATCTGATTTCTTGGAAGAAATTGGACTTTTTTGCATTATACATACAGTATATGAGAGAGAATCATTAAGGATGGGCTAAAATGAGTTCATTCATTTGAGTGGATTTGACTACTCCCGAGCTAAAACCACTACAGTAATCTGAAACACATATTTTCAACACATTTTACAAAGATAAAGCAACCCTTCTCTTTACCTTGTACAGTGTAATCTCTTTCTCCACGTCATTGATGCTCTGATCATCATAGGCAGACGTCTTCTTGCTCACAAATGTCAAGCCGCCCAGTTTGTCACTGCTGTAGGATTTGTATGGTGAAGGAAGTTTCTCAAAGTCTTTTGCGTCCACATAGACGATGGATTTTTTGTAGTCGCTAGGGTAGCCCAAACTGTCTCCCCGGCCTGTGTTGATAATGGGACCCAGCGTGGG
ATCG/- ACTGTGACTGGGATGATGGTGGTATCAGATTCTCCAGATTCACTCTCACTGGAGTCAGTCTCCTAACAGAAAACACAAATGATGGGCTACATATCGGACAATATGACATTTGTGGATTCTCTGCTACAGTAACATTGGGTAGCAACACTGTGAAATGTCACTGGTCGAAAATCCTGCTTCTTACCAAATCAAATATGTTGTCATTTACTACAGGATCCGGAATTAAAGTCTATGTAAAATCACAATTTACTATGTTTATTTTGTCCAAGTTAATTTACTGAAAAAACTGTTTTGGTAATCCTTAATCAAAGTCTAACCGCTTCCATGTTTGGAGTGGCAGTCCTTCTCTGCTTCTTCCTAGCTACAGTTTTCTTAATTGTGACCCTTATTGTAAATTGTTAGGATAGGATTTAAACATAAAAGAATCTTCGAATCATATTCACTGTGACTGTTTTGCATTCAGTCTAAATAGCCCAATTATCTGGTAATGTTCAATATAT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| spp1zf3367/zf3367 | Homozygous | ♀+/- ♂+/- | Fig. 7 from Bevan et al., 2019 | ||
| spp1zf3367/zf3367; gl23Tg; pd1028Tg | Complex | Fig. 7 from Bevan et al., 2019 |
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Supplemental Information
- Genotyping protocol
- None
- Bergen, D.J.M., Tong, Q., Shukla, A., Newham, E., Zethof, J., Lundberg, M., Ryan, R., Youlten, S.E., Frysz, M., Croucher, P.I., Flik, G., Richardson, R.J., Kemp, J.P., Hammond, C.L., Metz, J.R. (2022) Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease. BMC Biology. 20:21
- Bevan, L., Lim, Z.W., Venkatesh, B., Riley, P.R., Martin, P., Richardson, R.J. (2019) Specific macrophage populations promote both cardiac scar deposition and subsequent resolution in adult zebrafish. Cardiovascular research. 116(7):1357-1371
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