Genomic Feature
zf3355
- ID
- ZDB-ALT-220119-13
- Name
- zf3355
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- embryos treated with
- Lab of Origin
- Current Source
- Other Pages
-
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 9: 35059294 - 35059300 (GRCz11) (1) Details
- Nucleotide change
- GCCAACA/TG
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 2 bp inserted / 7 bp deleted in Exon 2 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
TGTCAATACTGTTCCTTTATAAATTTCCTCATCAAATTCCTACACACTATTTTTCACATAAGAGTATATTTGAACTAAATCATATATCTGTCACACTGCTACCTCAAAAACAGCATCAGTCATAAAAAAAAATCTCATAATAATCAGTCACAACATAGTACCTGACTTGCTTATGTAATGCTCAGAATCCCCATGGTCATTAATTACTTTGACTGTCATTATATAATTGATTTTAATTACTAAAGTAATCACGATACAATAATGTTTAACAACCTGCACGAGCTATTGACGACTAACGCTGACACCGCAGCAGAGCTCAATGTATTCGCACGTCTTGTTTCATATCTCTTTTCTCTCTCATTACCTCTTGGCAGTATTGAAGGATGCCCTCTTTGGTGCTGATGCAGCTCTTGGTGCCAGTTGGATCAGGCTCCCACTTGCCACTCTGGACGTTGATATGCATGTTGAGTTTCCCACAGAACATGGCCACCTGAGGCTCC
GCCAACA/TG AGCCCACCGAGTCATCCGACGGCACCTGCCAACAGCACAACCGGCAGGAACATGAGGAACCATTATCACATAAGCCAATGATCTTTAGACAGCTTCACGATGGGGCCTTTGTCAGCAATTATCGAGTATATGATTTGCTTGATGAGTTGATAAGAATATTAAGTAGATCTTTTTTTTTTCTCTCCCAAAAATTGACATTCACATTCAGTTTTTTATTATGTCAAAGACAAAAGAAGATATTTTGAAGAGTGTGGGAAACCAGTAGCCATTGACTTCCATAACAATATGTATATATCTATTTCATCTAGTGTTCAAACTACTTGTTTAAATTGAGCTGAACCTACACAATTTTTTTTTGCTTTTTTTGGGGGGAAAACTTAATTGTTTTATGTTCAATCAACTAAAATTTGTAACAACTAATTTTGTTGTCCCAATACAAATTGATTGTGTGGAGTCCAGCATTTTCTACAGTGTATGTAAGTCAATGGCTACCACTTACC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| appbzf3355/zf3355 (AB) | Homozygous | ♀+/- ♂+/- | 6 figures  from Banote et al., 2020 | 2 figures from Banote et al., 2020 | |
| appazf3579/zf3579; appbzf3355/zf3355 (AB) | Complex | 4 figures from Chebli et al., 2021 | Figure 6 from Chebli et al., 2021 |
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Supplemental Information
- Genotyping protocol
- None
- Rahmati, M., Chebli, J., Banote, R.K., Roselli, S., Agholme, L., Zetterberg, H., Abramsson, A. (2024) Fine-tuning amyloid precursor protein expression through non-sense mediated mRNA decay. eNeuro. 11(6):
- Chebli, J., Rahmati, M., Lashley, T., Edeman, B., Oldfors, A., Zetterberg, H., Abramsson, A. (2021) The localization of amyloid precursor protein to ependymal cilia in vertebrates and its role in ciliogenesis and brain development in zebrafish. Scientific Reports. 11:19115
- Banote, R.K., Chebli, J., Şatır, T.M., Varshney, G.K., Camacho, R., Ledin, J., Burgess, S.M., Abramsson, A., Zetterberg, H. (2020) Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish. Scientific Reports. 10:10127
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