Genomic Feature
mi4008
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 7: 38752667 - 38752677 (GRCz11) (1) Details
- Nucleotide change
- CAGCTGAAGCTACCGGA/TGT
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 3 bp inserted / 17 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
ATTAACAGTTTGAGAATATGTGCGACTACAGAGGGTAAGTGGGATGCATGTTTGCTTACTTTGGTAACAGAATATGCTTGTTGTAACAAAACGAGACATTCTGTTAAGGTGAGTCCTTTCTACATTGTAAAATAACCCAAATTGTTTAATGTGTGATTGATAGGGGACTGTTTCATAAATATTGGAGCAAAGTATGCTGGTAAAGTATCTGTCACCAAGTCTGGAAAGGCATGCCAGTACTGGAAAAGCAACTTTCCCCACAAGATTGAGTATGCACCACTACTCTCGTATTTTTATTGTACTGAACCACCTTTAACAGTGTCTAACTGTGTCATCTCCCAGTGTTGGCCAGTGGGGAAAAACATTTCATATTGATTGAATAGAAAACACAAAAGCCTTCAGTAAAGAAAAGGTTGTTTTGTTTTACATGCCTTTAGTGATGTTCCTCTGTCTTATGATCCATTTGTTTCCCCCGCAGCGAATTTAATGTGACACAGCTG
CAGCTGAAGCTACCGGA/TGT GAACTTCTGCAGGAACCCAGATAAGCACAAAGATGGCCCTTGGTGTTTTACCAGAGACCCGACTGTCAGGAGGGAGACCTGCAATGTGCCAAAATGTGGTAGAGAAAACTTACTAAAACATAACAGCAAAATGTACTAAAGTGCAGTAACTGGCAGTCAGAAATTTGAAATCAATCAAAACTGTATTATTTATAGCATTTGTTACCATCACCTGTTTGGGCATTGTGTTTATTGCACAGTCCAGGCTTGAGTTAAAGGGATTATTTACCCCAAACATCATTGACTCACCCTATACTCGTTTTAAACATTTCTTTATTCTGTTAAACACAAAAGAAGATATTTTGAAGAAAGCTGGAAATATGTAACCATTGACCTCTATTCATTCATTGACTTTCAGCTTTTTTTTTTTTTTGAGGCTCAGTAAATCATGAATAAGTTATCATTTTTGGTGAACTATCCCTTTAAGATTGTCTGCAGAGTGCCTTTAATTATCTTTTTAC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| f2mi4008/mi4008 (AB/TL) | Homozygous | ♀+/- ♂+/- | 2 figures  from Grzegorski et al., 2020 | Figure 3 from Grzegorski et al., 2020 | |
| f2mi4008/mi4008; la2Tg (AB/TL) | Complex | Figure 6 from Grzegorski et al., 2020 |
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Supplemental Information
- Genotyping protocol
- None
- Grzegorski, S.J., Zhao, Y., Richter, C.E., Ku, C.J., Lavik, K.I., Paul, D., Morrissey, J.H., Shavit, J.A. (2022) Genetic duplication of tissue factor reveals subfunctionalization in venous and arterial hemostasis. PLoS Genetics. 18:e1010534e1010534
- Grzegorski, S.J., Hu, Z., Liu, Y., Yu, X., Ferguson, A.C., Madarati, H., Friedmann, A.P., Reyon, D., Kim, P.Y., Kretz, C.A., Joung, J.K., Shavit, J.A. (2020) Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish. Scientific Reports. 10:4049
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