Genomic Feature
hzm14
- ID
- ZDB-ALT-200702-2
- Name
- hzm14
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- embryos treated with
- Lab of Origin
- Lopez-Schier Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 15: 28199297 - 28199305 (GRCz11) (1) Details
- Nucleotide change
- ACGTCGGTG/TC
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 2 bp inserted / 9 bp deleted in Exon 1 (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- None
- Flanking Sequence
-
GATACATGACTTTTGAATTTACTTTTTACTGTAATCGCAATAGGATTTTTATTGGACACATGAATTGATCTTATGCTCACAAAAATAGCAACACTCAAAATGTACTAAAATTTTTCAAACTGTGTCCGTCTTTGAAATGTTTTTTTAATACTTTTAAAGGCCCACATGAACAAAAACCACACTTCCTCTGAAACGTTCCTCACCTGTTTTCTGACACCAGTATCTGTTCAAGCAGTTTGGCAGACTCGTATGTGATTTCCACAGCAGGAGTCTGCATCAACTGCAAGAGCAGCTCCAAACCGCCATCCAGCCGGATTCTGTTGCAGATCTCCTCCGCTACCCGTCGGCCCACTGTGGGCAAGACCCAGGCCTCCTCAACCAGCTGGAAAGTCTCAGCAATGGCCCGGCGGGTCTCTTCCAAGTCCCCCGTGTCTTTGGAAGACCTCAGTGTTCTGATAGCAGAGCGCAACGCGGGGAGAGAGCCGTCCAACACGGCCTGG
ACGTCGGTG/TC CTGATCCCCGGGGACACAGCCCTGGGGTCGGGGGCCGTCCTGCGGTTGTGCAGCCGACTACTGACATATTCGGGAACCGTGAGCCTGTCGGAGCTAAACATGGAGAGATAACGGCAAATCTTGCTAAGGTAAACGACGAGGGACAAAAACATCTACCAGCTGATTGTCTGTTGCTACAATCGTTCTTATGTTTCTTTGTTTATCGACTGTGACGGAAATTTAACTCATTCCCTTTATTAGCTGCACTCTTATGCGAGATAATTGATTATCAGCGACTGTTATCATCACAGCACATTATCCCGCTGATGTCAGAAACAAAATATAAACACAAATGACGTCAGAGCCTTTGTGATCAATCCACCTTCAGAAGGAGACCGCGACGGTTATTTAAAACCTAAATAGCATGCTGAATCTTGGTATTTTGAGGAAATATAGACATTCGCCGGCTTGTATTGCTGTACACTGGAAGTCGATTGTAAATTGTCAGACAAAGACGACTG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| cntnap2ankhgn39dEt; sarm1hzm14/hzm14 | Complex | Figure 1  from Asgharsharghi et al., 2021 |
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Supplemental Information
- Genotyping protocol
- None
- Asgharsharghi, A., Tian, W., Haehnel-Taguchi, M., López-Schier, H. (2021) Sarm1 is dispensable for mechanosensory-motor transformations in zebrafish. microPublication. Biology. 2021:
- Tian, W., Czopka, T., López-Schier, H. (2020) Systemic loss of Sarm1 protects Schwann cells from chemotoxicity by delaying axon degeneration. Communications biology. 3:49
- Tian, W., López-Schier, H. (2020) Blocking Wallerian degeneration by loss of Sarm1 does not promote axon resealing in zebrafish. microPublication. Biology. 2020
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