Genomic Feature
vp34rc1
- ID
- ZDB-ALT-200310-2
- Name
- vp34rc1
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Parichy Lab
- Current Source
- Other Pages
Notes
Comment | Citation |
---|---|
This mutation was created in fish doubly homozygous mutant for thraa (vp33rc1) ... | Saunders et al., 2019 |
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 19: 17524376 - 17524418 (GRCz11) (1) Details
- Nucleotide change
- GCTTTGTCTCCACAAACAACACACAGCTCATCCTTGTCCAGGT/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 43 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
ACTGACTGACTGACTGACTGACCGACACCCCCACACACCCCTATCCCTCAACCCAACCAATAATGTTTTAAAACGCACAGATTTACCTGTAACCACCCACTTCCCTACACCCAACTGACAGTGTTTTCCTAAAAAAGATAAGCCCTTATAGTAGCCAGATTTTACCACATTTTCACGCTCTTATTTACTAGTTTGTTTTACCTTTCTTTCTGAAACTATCATGCTCAACTCCGCTCTGCATCTCAAATCCTCCAACGTACACAGCAAGCCACTGGACAAACTGGTAACAGCTGAGTTGCGCACAAAGAAACGGCGTCATACCACCCCGTAGCATTCATTTTAAAGATGAAACGCATCCATATGTTTCTCTGGCTACATAATTTGCTATCTCCAGAAATAAAGGAGTACGTTTTCAGAATAAGCCAATGTTGCATAGGGCAAGAGAAAAAAAACTCACTTTGCAGCCCTCACATGTAATGCAGCGATAGTGATAACCAGTT
GCTTTGTCTCCACAAACAACACACAGCTCATCCTTGTCCAGGT/- AACTTGGTATGTACCCTGTTAGAGTAACAAACACAACCCATTAAAACGAAACACTTGTCATAACACCATAATAATCATGACATGATTCATGTAATAAATATGAAACAGATTTTATTCTTTATTCTGCATTCTTATGAAAACTTTATGTTAAATGTCAATCAGTTTATGTCATTTTAAATGCAAAGATGACTGATTTATTGAGATGTCTTTTTCATGACAACAAAACCTGTTAGTGTCTTAGTCATGACAATGTGACATTACCAAGACAACAGACCTCGTCATAAATCTGTTATGAACATGATTGTTATGATGAGGCTATTCTACTGTAATTTTGTATGAATATTTTTCAAATCACTTATTTTTTCCAGTGGAACAACTAAATACGTAATTTAATGACTCATTAAAAGTGCCAATACTCTTGTCAAATAATTTTAAGCATCATTTTAACAGCATCATTGATATTTTTCATGATCTCTACAATAGTGGTACAAATTTTATTT - Additional Sequence
- None
Fish
Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
---|---|---|---|---|---|
thraavp33rc1/vp33rc1; thrabvp31rc1/vp31rc1; thrbvp34rc1/vp34rc1; wprt8Tg (AB) | Complex | Figure 7 from Saunders et al., 2019 |
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Supplemental Information
- Genotyping protocol
- None
- Harper, M., Hu, Y., Donahue, J., Acosta, B., Dievenich Braes, F., Nguyen, S., Zeng, J., Barbaro, J., Lee, H., Bui, H., McMenamin, S.K. (2023) Thyroid hormone regulates proximodistal patterning in fin rays. Proceedings of the National Academy of Sciences of the United States of America. 120:e2219770120e2219770120
- Saunders, L.M., Mishra, A.K., Aman, A.J., Lewis, V.M., Toomey, M.B., Packer, J.S., Qiu, X., McFaline-Figueroa, J.L., Corbo, J.C., Trapnell, C., Parichy, D.M. (2019) Thyroid hormone regulates distinct paths to maturation in pigment cell lineages. eLIFE. 8:
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