Genomic Feature
zju16
- ID
- ZDB-ALT-200211-2
- Name
- zju16
- Synonyms
-
- zju1 (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Jinrong Peng Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 12: 47663522 - 47663535 (GRCz11) (1) Details
- Nucleotide change
- GCTCCTCCGGTCCG/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 14 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
TTTTATTATTGATTATAATAATTTATAAATTATGATGATATTAATAATAATAATAGCCTAATAATAATAATAATAGCCTAATAATAATAATAATAATAACAATATTGCTGTTAATATGCGACAGAAAAACTTTTGCCATTGAATAGTTCCCTTCCCTCTTCCTTTATGTCCATGAAAGTGCCTGTTTAATCAGGTGCATCCTGACTTTCCCCTGCAGTTTCTTCGTGATTCTTCATCTCGGAGCCAATCAGCTGTCGCGTACCTGCAGGAAGTTTGACCCGTTATTCTCCTCCCTCAGAGTGACCTCCAGCCGCTCTCCGCACACACGCACAGACTGCATGGAAGTCGGAGCAGAAGCCGCACGAGTTTATCCAGGAGCAGCAGCTGTTCATCCATCATGCAATTCCAGCACCCGCACGCGCCTCTGTACGCACCGACGCCCGCGCCGCCCGCGCACCCGACGCCCTTCTATATAGAAGACATCTTGGGAAGAACCGGGA
GCTCCTCCGGTCCG/- GTGGTGCCCACCCCGACCCTGCCGTCCCCGAACTCCTCTTTCACCAGCCTGATCCCGTCTTATCGGACACCGATCTACGAGCCCACGCCGATACACCCGGTTCTGTCCCAGTACGTGTCCATGTACCCGTTCCAGCGCTCCGTGGGAGACTTTGCGCATGCGCTGATCCGCCACGACCCGCTGGGTGAGCCTCACAGCACATCGCAATCTGTTTCTTTTGCTCAAATGTAAATTAGCAGTGTGATTTTTTATTTATTTATGCATTTGAGTTGCATTATGGGAGCTTGATCTTTCTTACAACAATTTTTAACATTGAAAACTTGAAAAAGTGACTTATTTATACTTTCAATAGTTTAAAGTAATAAATTGTCAGGGTTGGTTATGCTACAGAAACCTTGTACTTCTAGTACATTTTCTGTCATTTACAGACTTATTTTCTATATAATAATCACATTATATTATAATTACATTATTCAAACTACTGAAATGTCAATAAAAGT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| hhexzju16/zju16 | Homozygous | ♀+/- ♂+/- | 2 figures from Gao et al., 2018 | 4 figures from Gao et al., 2018 | |
| hhexzju16/zju16; gz15Tg | Complex | Fig. 3 from Gao et al., 2018 | Fig. 3 from Gao et al., 2018 | ||
| hhexzju16/zju16; jh12Tg; s928Tg | Complex | Fig. 5 from Gao et al., 2018 | |||
| hhexzju16/zju16; s928Tg; zju19Tg | Complex | Fig. 5 from Gao et al., 2018 | |||
| hhexzju16/zju16; zf3097Tg | Complex | Fig. 4 from Gao et al., 2018 | |||
| hhexzju16/zju16; zju18Tg | Complex | 2 figures from Gao et al., 2018 | Fig. 3 from Gao et al., 2018 | ||
| hhexzju16/zju16 + MO1-pdx1 + MO3-cdx1b | Complex | Fig. 8 from Gao et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Jin, Q., Hu, Y., Gao, Y., Zheng, J., Chen, J., Gao, C., Peng, J. (2023) Hhex and Prox1a synergistically dictate the hepatoblast to hepatocyte differentiation in zebrafish. Biochemical and Biophysical Research Communications. 686:149182149182
- Gao, C., Huang, W., Gao, Y., Jan Lo, L., Luo, L., Huang, H., Chen, J., Peng, J. (2018) Zebrafish hhex-null mutant develops an intrahepatic intestinal tube due to de-repression of cdx1b and pdx1. Journal of molecular cell biology. 11(6):448-462
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