Genomic Feature

icm26

ID
ZDB-ALT-191001-4
Name
icm26
Synonyms
None
Affected Genomic Region
Construct
None
Type
Allele with one deletion (1)
Protocol
embryos treated with
Lab of Origin
Wyart Lab
Current Source
Other Pages
Notes
No data available
Genome Browser
Genome Build: GRCz11Chromosome: 8
Variants
Variant Type
Small Deletion
Variant Location
Chr 8: 47063590 - 47063594 (GRCz11) (1) Details
Nucleotide change
TGGTG/-
Variant Notes
mutant Espin proteins lack the conserved Actin-Bundling Module.
Effect on DNA/cDNA, transcript, protein (from publications)
DNA/cDNA Change
5 bp deleted in Exon 11 (1)
Transcript Consequence
Frameshift (1)
Protein Consequence
Polypeptide Truncation (1)
Sequences
Flanking Sequence
TAAATGTCACTTTAAGCTGTATAGAAGTGTCTTGAAAAATATCTAGTCAAATATTATTTACTGTCATCATGGCAAAGATAAAATAAATCAGTTATTAGAAATTAATAGAAATGAGTTATTAAAACTATTATGTTTAGAAATGTGTTGAAAAAATCTTCTCTCCGTTAAACAGAAATTGGGGAAAAATAAAAACAGGAGGGCTAATAATTCTAGGGGGGCTAATAATTCTGATTTCAACTGTGTATTTTCTTCTAGAACCTTCAATTCTGCTCATTTTCTCTTACAGGGGGAAAGTCCATCATCGCCGCCAGAGCCTCTGCCAAAACCCAACGACACCCAATCCGCGAAGCCAGAATCTCCACCGCCTGCTTGTCCACCGACGCCACCCAATCCCACAGCCAGCAGGTCGTCACCCCAGAACCTGTCCACTTCACAGAGCAGCGACCAGCTCACAGCTGCGGTCAACGGTAACACGTCTGTCGTCCAGAACAAGACCAGCG
TGGTG/- GACGTGGAGAGTTTGGTGCCCACGCACGACGAGCAGGGCCGAGCCATTCCAGAGTGGAAGAGGCAGGTGATGGTCCGAAAACTGCAAGTGAAGATGCAGGAGGAGGAAGAGAACAAGAGAAAGGTGAGTGAGAGAATGTTTCCAGTGCCAAACATGAGTTGAAGTCAAAACTATTAGCCTTTTTTTTCTTTTAAATATTTCTCAAATTATGTTTATTAGAGCAAGGAAATTTTCACAGTATTTCCTATTATATTATTTCTTCTGGAAAAAGTTCTTATTTGTTTTATTTCGGCTACAATAAAAGCAGTTTAAATTTTTTAAAAACTATTTTAAGGGCAATATTATTAGCCCCCTTAAGCAGTATTTTTTTTATTATTATTATTTTTTGATAGTCTACAGAAGAAACTATTTAGAAATGTGTTGTTAAAATCTTCTCTCCGTTAAACAGAAATAGGGGGGGAAAGATTCACAGGGGGACTGATAATGTAATAATGCAGGAG
Additional Sequence
None
Fish
Fish Genomic Feature Zygosity Parental Zygosity Affected Genomic Regions Phenotype Gene Expression
espnicm26/icm26Homozygous♀+/- ♂+/-2 figures with image from Desban et al., 2019
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Supplemental Information
Genotyping protocol
None
Citations
TSV
1 - 1 of 1
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