Genomic Feature
tju1
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 17: 20926911 - 20926914 (GRCz11) (1) Details
- Nucleotide change
- GACT/ATAGAAATAGA
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 11 bp inserted / 4 bp deleted (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
TTGTTTAGTTGTACTTTTTTAAATTAACTTTATCATATATTGTACCTATAATGTGGCTATTTCACACAGTCTCTCTCATTAACTAGCTTTTACTAACGCAATGTGTAAAGTGTTTTATCGTCACTTTATAATAATTTAGCAATTTAGGGTGTTTATTTTAAATATGAATATACAATACACAATTATTATTTTTTTGTTATAGCTGTTAGAAGTACTTTTTTACAGCTTTGGTCTATCATGATACAGCTTCAGCAGTTAATCGCAACAAGAAAATTTGATACTGGCAGAAGCCTAATACCAGTTGATGATACTTGCTCAAAATGTTATAATCACTAATGCTGACGTGTGTGCGCATGATTATGATTGTGCAGGTGGTCACTCTGTGGTACAGAGCTCCAGAAGTGCTGCTGGGGGCTTCACGCTATTCCACACCTGTAGATCTCTGGAGTATTGGCACCATCTTTGCTGAACTCGCCACCAAGAAACCTCTCTTCCATGGA
GACT/ATAGAAATAGA CCGAAATAGACCAACTCTTTAGGATCTTCAGGTAGACAAAGTTCAGGAATCAGTGTTGACATTTATTTATTTATTTATTTTTTATTTTATTTTTTTTTAACAGAGTTTTAAAAGTATAAAAGAAGTTTGAAAAGGTCAATTAGGGCTGTACTTGGTAACAAACTTATTTGCTCGTGTTAAACTGCACAGACATTAGGGTACAATATTGTATTTATAGTACAACATGTATTCTCTATGATAATATAATTGTTGTATTAGCGCACGTGTGAACATGTTTGAAAACCTTGAAATAGACATTCTCTTTTCTCTCTTACTCATGAAAACAATAATAAGTAAGGGAATATATTAGTAATTTTATAAAAGGGGAAATTATAACAGTAAGAGAAAATTTATAAAATGATAAAGTAACAATAAAGAAATGGTAACAATATTAAAAATGTTAACATTAACAAATAACCAAATAGCTAAAATTAAATCATGAACTAATGGACGATTAATGA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| cdk1tju1/tju1 (TU) | Homozygous | ♀+/- ♂+/- | 8 figures from 2 publications | 3 figures from 2 publications | |
| cdk1tju1/tju1; cu2Tg; jh1Tg | Complex | Fig. S2 from Jin et al., 2021 |
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Supplemental Information
- Genotyping protocol
- None
- Jin, M., Li, J., Hu, R., Xu, B., Huang, G., Huang, W., Chen, B., He, J., Cao, Y. (2021) Cyclin A2/cyclin-dependent kinase 1-dependent phosphorylation of Top2a is required for S phase entry during retinal development in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 48(1):63-74
- Hu, R., Huang, W., Liu, J., Jin, M., Wu, Y., Li, J., Wang, J., Yu, Z., Wang, H., Cao, Y. (2019) Mutagenesis of putative ciliary genes with the CRISPR/Cas9 system in zebrafish identifies genes required for retinal development. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(4):5248-5256
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