Genomic Feature
ch3
- ID
- ZDB-ALT-190703-4
- Name
- ch3
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one insertion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Robert Ho Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Insertion
- Variant Location
- Chr 5: 23152473 - 23152474 (GRCz11) (1) Details
- Nucleotide change
- -/GCTA
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 4 bp inserted in Intron 1 (1)
- Transcript Consequence
- Splice Site, Intron Gain of Intron 1, Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
GACATATTATTTTTTTCCTCCTAGAAACGCTTTTCCTAAGCAATAATGCGCTCTTGATCTATCCTAAAATTATCCGTCGAACGCAAAATAGCTTAAACCGCTTAATTTTATTAAACCTAAATATAACAAATAATTATACAAATAATTTAGATTTTAAATGAATTTAAACGCATGGCTTGTTTTCAGCCTTTTTAAAACAACATTATGAGTTTGGGGGATTATTGTTTTTGGTTCATATCTGAAGATCAGCTGGTTGAAACATTCATGCATTCATTTTTTTAATGCGCATCTTCCAGTCCACCGTAATTGAACTCAGACGGGAATATGGCGAATCCAATGTTCGAATCTCTACGGGCATGTTCCGGTGGCAATTCCCCCGCGATGGATTTCGAGAGGGATAAGGATTCAGGACATCACGGACGGAACAAAACCGGCTCCCCGCCACTACAAACTCAGCTCTCCCAACAGGTCAGCCATAAATGTGTGCAGCCTGCTCGAGTA
-/GCTA TACAAGACGAAATGATAAAAAAAAAAAATATGATGATGATGATGATGATGATTATTATTATTATTTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTAATATTAATATTATTTGGCCGTCACTGGTTTTCTCGTTTGTTTGTTTTTTAGGTAGCCTATGTTAGCCTATCCACACATAGGCTATTACAAGTGAATTAGTAATGTTTACTATAGTTATAGCAAAGACATTTTGTATAGCATCATATTCATTAATATAGGTGTGTATTTTAATAATTTATGTAGAACCTACCTATATGCTTCGTTCTACATAAATAATTTAAAAAGGGTGCCAAAAATAAGGCTTTGGCAAGTGTATATTAAATGTTAAGCTGATGCGCAAATCGTTTAATTTACTTTTAAATTCGATGCTGTTTTATTTAAAGTAGTTATTGTTTGTACTAATTAACGCATTATTTCTATATAAAAAAATC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| tbx5bch3/ch3 (AB) | Homozygous | ♀+/- ♂+/- | 3 figures  from Boyle Anderson et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Boyle-Anderson, E.A.T, Mao, Q., Ho, R.K. (2021) Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish. Developmental Biology. 481:201-214
- Boyle Anderson, E.A.T., Ho, R.K. (2018) A transcriptomics analysis of the Tbx5 paralogues in zebrafish. PLoS One. 13:e0208766
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