Genomic Feature
ed9
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 21: 6137568 - 6137571 (GRCz11) (1) Details
- Nucleotide change
- GGAC/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 4 bp deleted in Exon 2 (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
ACCGGAAGCTCTGGCGGCGGTGAAAAGTACGAATATTTTACTAATTTTATACACTTAACGTTCATTTACACTGTTAAATCTCGCATTTTATTACATTTTAATATACAAAGCACACATTTGTACTGCTATAACATAGCTAGTCTCCAAAGCGACGCTGTAAATGTGATGTTTGTGTGGGGGTCTGGATTTGTGTCTTTGTCGGGCCGAAAGAAAACGCGAAGTGATCCACACACTCAAAACAGCGTCATAAAAGACCAAATAGTTCTTTAAAACAAGCTTAATTATAACATAAATCAGTAAATAGCGGATTTGTAGTTGTACTTAGCGTGATATGTGTAGGCGGAATGAAGTAATATCGCCTTGTTGTAAAACATGAGTGTGTATTTGTGTTGTTTGTGTTCAGGCCGGACAGAGAGACCGCCATCATGTCCAAATACTACGATGGCGTCGAGTTTCCCTTCTGTGATGAATTCTCCAAATATGAGAAGCTGGCGAAGATC
GGAC/- AGGGCACCTTTGGGTGAGTATTTGATGTTTGTGTGTGTAAATATACCATAATGTTTATCATCCAGTAACAGACCATTTTCACATGGCGTCCGGTTTCACTCCATGCAGTGTGTCGTTACTTCCGCCTACATAGAAATCCCCATATGGCCCGTTTCCACTGAGTGGTACGGTTCGGTTCGGTTTGGTACGCTTTTATTACAAAAGGTGGCGGTAGGACATAATTCATTCAAATGAAGAAACTGAACAAAACATTAATATTTCAGTAAATAATAAATGATGAAACTGGTTGCATTTGTAGACATAATGGAAATGTTGCAAACACATGCTTTCCCTGATAAACCATAGCTTATTCATGTTCTTAACAACTTAATCATTTTCAAACTCAGAAAACAATTCAGTATTGAAAGAGACACATTTGGACACATGGCCAATACCAATAATAGTGTTAAATCAGATCGTGCAATCTTAAAGGGCCATGAAACCCCCTCGTTTCAGCAGGG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| cdk9ed9/ed9; i114Tg | Complex | Fig. 5  from Hoodless et al., 2016 | Fig. 5 from Hoodless et al., 2016 | ||
| cdk9ed9/+; i114Tg | Complex | Fig. 5 from Hoodless et al., 2016 | Fig. 5 from Hoodless et al., 2016 |
1 - 2 of 2
Show
Supplemental Information
- Genotyping protocol
- None
- Kaveh, A., Bruton, F.A., Oremek, M.E.M., Tucker, C.S., Taylor, J.M., Mullins, J.J., Rossi, A.G., Denvir, M.A. (2021) Selective CDK9 inhibition resolves neutrophilic inflammation and enhances cardiac regeneration in larval zebrafish. Development (Cambridge, England). 149(8):
- Hoodless, L.J., Lucas, C.D., Duffin, R., Denvir, M.A., Haslett, C., Tucker, C.S., Rossi, A.G. (2016) Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo. Scientific Reports. 5:36980
1 - 2 of 2
Show