Genomic Feature
ncv101
- ID
- ZDB-ALT-170522-16
- Name
- ncv101
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Mochizuki Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 18: 37355212 - 37355236 (GRCz11) (1) Details
- Nucleotide change
- CCGGCCACCAGATCGTCCATGTTCG/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 25 bp deleted in Exon 1 (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
GTATGACTTTAGGTTCAGACTTTATTTTACATTTCTTAATTACAAATCAAGAATGACATTTCACTTTTATTTGACTATTTATGACTTTCAGTAATATGCAATCGGCCTTTATTTTCCTGCATAAATGTATCTCTAAATACGATGTTTACAGTTCTTTAAGCATGCAAAAACAAACAAATAAAACTAATAAAAATATTTTAAATCTGTGACTGTGTCATTACAAACTATACGAAAATACTACGCAGTGACACTGCAGGCTGAAAGTGTGCATTGCCCCGGCGCCAGTTGCAGTGTCAGGCGCAGGAAAAGTTTGTGGAAACTGTTTGTGGTTTCTGAGGGGGTGGTCTCTTACTTGTCTGGAGTGGGACTTTGGCTCTGGCGGCGTGAAGAATGAGTCTGGCAGCTTTCTCAACCTCATCGGCACGGAAGGGGGGACGATGGTGTTTTTCGGGTTCATCACAGCGTTAAAAAGAGCCTCCAGATCGGTCTCGGAGTCTCCC
CCGGCCACCAGATCGTCCATGTTCG/- CTGGAGGGTTGTGCTGGTTCGGATCCATGACTCCAGATAAAAGTAAAACTCTTCTTTCTATCCAACTGAAACCGTTTTCAAGGAAAGTCGGCTGCAACCATACAAATGGCGAAAATTTTAATCCAAAACAACCCAAAAAGATGTTCTGTGTCCGGCCGCTTTATCAATTATCCAAGCCTTGCGAAGGAAAAAAATTGGCAACGTTGTGTTTTGCTGCTTGCCAAAAACACCCAAATAAATGTGGAAACGCGCATATCTACAAAACTGTATCTCTAAAACTTTTTCTAAGGTGTCTAAACTTTCTAAAATCGTTGTCTGTGTTGCTTTTCCAGTAGTTTACGGCTCTTCTAACGCAGGCATTGGTAGTGACTGTACTGCGCATTGAAAATCACAGCCCTCTCACTAACCTAACTAACTTTTTTTTCTCTTCTTCCAACTTCTGAAACTTTGGGCAGGACATCAAACTTTATGAGTCATGTGACCGCTGACTCAGAGGGGCG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| yap1ncv101/ncv101; ncv1Tg; ncv36Tg; nkuasgfp1aTg | Complex | Fig. 2  from Nakajima et al., 2017 | |||
| yap1ncv101/ncv101; ncv12Tg; ncv1Tg; nkuasgfp1aTg | Complex | Fig. 1 from Nakajima et al., 2017 | |||
| yap1ncv101/ncv101; y1Tg | Complex | Fig. 7 from Nakajima et al., 2017 | Fig. 7 from Nakajima et al., 2017 |
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Supplemental Information
- Genotyping protocol
- None
- Grimm, L., Nakajima, H., Chaudhury, S., Bower, N.I., Okuda, K.S., Cox, A.G., Harvey, N.L., Koltowska, K., Mochizuki, N., Hogan, B.M. (2019) Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk. eLIFE. 8:
- Nakajima, H., Yamamoto, K., Agarwala, S., Terai, K., Fukui, H., Fukuhara, S., Ando, K., Miyazaki, T., Yokota, Y., Schmelzer, E., Belting, H.G., Affolter, M., Lecaudey, V., Mochizuki, N. (2017) Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance. Developmental Cell. 40:523-536.e6
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