Genomic Feature
umo6
- ID
- ZDB-ALT-170404-9
- Name
- umo6
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Wei Ge Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 18: 39631858 - 39631862 (GRCz11) (1) Details
- Nucleotide change
- GATCC/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 5 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
TGATAGCTTTAGATTTATTAATGACAATAATGCATTTCATAATATATAATACATTCTTACTTAATTCAGTTTGCACTTAAAGGGATAGTTCACCCAAAAACTATTCAACACAAAATGTTAGAATGTTAGAAACCTGTAATCATTGACCTCTATAGAAGGAAAAATAAATCAAAGTCAACTGTTTCCAACATTCTTCAAAATATCTTCTTTTGTGTTGAACAGATAAAGAAACGGGTTTGTGACTAATGAAGACTAATGATGGTAGATGAACTGTCCCTTTATTAAGTATGTTGTTTCAATGTAATTTGTGCTGTTTTTCAAAGTATCTGAAAGTGTCTTTATTTTTCATAAGAGTGTTGTGTGTGTGTGTGTGCGTGCGTGCGTGGATGCGTATTTGTGTGTTTCTGGACTCACCTGCTCAAGATGAGAGTTTCCTCACCATTGATCCAGACACGCACAATGTCTCCATACTTGCTGTTGTAGTAGTTGCTGGCAGTCCC
GATCC/- CAGACCAGATGAACCGACAGTAGGAGACAACAGGACCCAGACCAAAAAAGAAAGAAGGACCTAAATGAAACACATTTTAGCAAGTCAGTGACATGACATCATTGATCAAAGTCTATTTTAAAGCAGAACTATGTAAGTTGTTTACCTTAAAATAAAGTTCCTATAAAATTATATCAAGTGGTAAAACGACTTTTAAGTTTGAATTCTGACGCTGGGGCTTCCAGAAAGTTGCAATGTGTTGCCTTAAAGGAACACTCTACTTTTTACAATCCCCCATTAGCATCATTACCATTAGCATCTTGCTCAAAAATATTCAAAAGCTTGACTAAATACAACATGTAATAAGACCGACAGAAAATTTAAAGTAGCTTTTTTCTGGGTCAGAAATATGATATGGCTCAGAAAATATTCTCATTCTGGTGTAATAATTCAGGAAATTTGATTTCGCACCATGGCTGCTGCAGGCACAATGTTATTACACAATGCCTATAAAAAGTCTC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| cyp19a1aumo6/umo6 (AB) | Homozygous | ♀+/- ♂+/- | Fig. 2  from Lau et al., 2016 | ||
| cyp19a1aumo6/umo6; zf45Tg | Complex | Fig. 7 from Qin et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Qin, M., Zhang, Z., Song, W., Wong, Q.W., Chen, W., Shirgaonkar, N., Ge, W. (2018) Roles of Figla/figla in Juvenile Ovary Development and Follicle Formation during Zebrafish Gonadogenesis. Endocrinology. 159(11):3699-3722
- Lau, E.S., Zhang, Z., Qin, M., Ge, W. (2016) Knockout of Zebrafish Ovarian Aromatase Gene (cyp19a1a) by TALEN and CRISPR/Cas9 Leads to All-male Offspring Due to Failed Ovarian Differentiation. Scientific Reports. 6:37357
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