Genomic Feature
ko322
- ID
- ZDB-ALT-140411-5
- Name
- ko322
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Kawahara Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 3: 54617729 - 54617738 (GRCz11) (1) Details
- Nucleotide change
- ATTACGACAA/-
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 10 bp deleted from position 179 to 188 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
CGTAAAGGATCACGATGGACAGCAAGATGATGCTAAAGATGGTGACAACAAACCGGATGTAGTATCGGGTGTTGAGGGGCAAAACAGCTGAGCAATCATCCAGGTTATTAATACAGTTCCAACCTATAATAGGAAGACCTCCTAGAAGAATGGACATCACCCAGCATGCTCCGATCAGAAGAAACATGCGGCACGTTTTGTTGGATCCGTAAACCTTGACCTTGGTGATGGCGATGTAGCGCTCGATAGCAATAGCCAGCAGGCTGAAAACGGAGGCGGACAAAGCAATGAAAGCAGTCCCCTCTCGTATGAACCACTGGACAGGAGTCAAATGAAATGTCCTAGGGCCAGACAGGAAGATGTTGGCAATGTATGCAGAGCCAGCTAGTAGGTCCGAGAAGGCCAGGTTCCCAATGAAGAAGAACATGGCTGAGTGGAACTTTTTATTCCTAAACACAGCGATGAGCACTAGGAGGTTTTCCAAGATGATGATGCTGCAG
ATTACGACAA/- ATAAAATGTTCAGGGAGCTCAAGCTTTGTTTGCTCTCGATGCGGTCTCTTAGTTCCTCTGCGGTCATCTCCTTAGCAGTGAGATAGTGGACCTGGATGAGGGTCTTGTTGAAGTACTGGGAGTATTTGCTCATGGTGACAGCTTGGCAAAACCCCGCAAACAGACGGCAAGTAGTCATTCAGAGGGCAGCTTTTTTTTGAGCTTGTCTGGGCCAGGCACAGGAAATGAGACGCCCAGCCCGAAGTCACGTCTCAGCGGCCCAGGAAGCTCCTCTGTGTCACCTGGAAACAAATACAAAAGAGACAATTACTGACAGGTCAAATGTTAAACATGGACTAAAAACAAATCAAGTATACACTTAAAGTTGTTGACAGTTCTGGACCTCTTACTAACTGCACTAATCAACTTGATTAAGTGGGATGGGCACAACAACACAAACCAATTTGGCCAGGACTACCCAGGTTTCCAAACAATGGAAATAGTAGGACTGTTCATTTAAT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| s1pr2ko322/ko322 | Homozygous | ♀+/- ♂+/- | 6 figures  from 3 publications | 2 figures from 2 publications | |
| s1pr2ko322/ko322; ko07Tg | Complex | Fig. 3 from Hisano et al., 2013 | Fig. 3 from Hisano et al., 2013 | ||
| s1pr2ko322/ko322; ko07Tg + MO1-s1pr2 | Complex | ||||
| s1pr2ko322/ko322; y1Tg | Complex | Fig. 3 from Hisano et al., 2013 | Fig. 3 from Hisano et al., 2013 | ||
| s1pr2ko322/ko322; ko07Tg + MO1-fn1a | Complex | Fig. 3 from Hisano et al., 2013 | Fig. 3 from Hisano et al., 2013 | ||
| s1pr2ko322/ko322 + MO1-fn1a | Complex | Fig. 3 from Hisano et al., 2013 |
1 - 6 of 6
Show
Supplemental Information
- Genotyping protocol
- None
- Hisano, Y., Inoue, A., Okudaira, M., Taimatsu, K., Matsumoto, H., Kotani, H., Ohga, R., Aoki, J., Kawahara, A. (2015) Maternal and Zygotic Sphingosine Kinase 2 are Indispensable for Cardiac Development in Zebrafish. The Journal of biological chemistry. 290(24):14841-51
- Hisano, Y., Inoue, A., Taimatsu, K., Ota, S., Ohga, R., Kotani, H., Muraki, M., Aoki, J., Kawahara, A. (2015) Comprehensive analysis of sphingosine-1-phosphate receptor mutants during zebrafish embryogenesis. Genes to cells : devoted to molecular & cellular mechanisms. 20(8):647-58
- Hisano, Y., Ota, S., Takada, S., and Kawahara, A. (2013) Functional cooperation of spns2 and fibronectin in cardiac and lower jaw development. Biology Open. 2(8):789-794
1 - 3 of 3
Show