Genomic Feature
zm197263Tg
Notes
Comment | Citation |
---|---|
The ZM_197263 mutation contains a retroviral insertion in the 5'UTR of the ... | Zaucker et al., 2013 |
No data available
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr: 3 Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
---|---|---|---|---|---|
notch3zm197263Tg/zm197263Tg | Homozygous | ♀+/- ♂+/- | 4 figures ![]() | 3 figures ![]() | |
notch3zm197263Tg/+ | Heterozygous | Unknown | 3 figures ![]() | ||
notch3st51/+; notch3zm197263Tg/+ | Complex | Fig. 1 ![]() | |||
notch3zm197263Tg/+; y1Tg | Complex | Fig. 2 ![]() | |||
notch3zm197263Tg/zm197263Tg; y1Tg | Complex | Fig. 2 ![]() |
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Supplemental Information
- Genotyping protocol
- None
- Sidik, H., Talbot, W.S. (2015) A zinc finger protein that regulates oligodendrocyte specification, migration, and myelination in zebrafish. Development (Cambridge, England). 142(23):4119-28
- Zaucker, A., Mercurio, S., Sternheim, N., Talbot, W.S., and Marlow, F.L. (2013) notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish. Disease models & mechanisms. 6(5):1246-59
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