Genomic Feature
rw685
- ID
- ZDB-ALT-090610-8
- Name
- rw685
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult females treated with ENU
- Lab of Origin
- Okamoto Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 20: 26783609 (GRCz11) (1) Details
- Nucleotide change
- A/T
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- T>A in Exon 7 (1)
- Transcript Consequence
- Missense (1)
- Protein Consequence
- Amino Acid Substitution: Trp>Arg at position 193 (1)
- Flanking Sequence
-
ATTATTTGGTTCATGTACAAAATTCGAACCCTTCAGAATATGTTGCTTTGAGTACAACAAAAGAATGTAACCATTAACATACAGGAATGATGTATTACACATTAAAAAGCATTTATGAATTATAAGGTATTTAAGTGAATGGGTGACATTCTCAAACTTCATTACTCTCCTTTTGGCATGAGCGTTAAAAAAAATAGGTTGACTTGTTAAGATTGACCAGCACTTATGACTGTTTTGATGAATGAGGTGCTGAAAATGTGAGGTCTGACACGTAGCAGTGGCTGCTGGTTACTGCATTTTTCAAAACCAAATGAAACCCAATCAGGCCTACTTTTACCAGAAAGTGCCCCCAAGTGAAAGTAACTGCAATATCTCTGCACCAGACTATGAATCGTGTGTGTGTGTGGTGTGTGTCTGACCTCTTCTAGGACTCTCATGATTGAACAAGATCCCATTCACAGCAAAGAGGTTATAGGCTTCCCTGAAGTTTATAACGATCC
A/T GTATGCATAGAGCTTAGCAGCACCTGCAAGAAAAAACAAAACAAAAAGAAAGAGATAGACAGTTGAAATACCGCTTTAAGAAATTTTATAAAAAGACATGATATTGGTGTCAAACACACATTTAACACCCAAATCTGATTTCCTATACAGTGCTCATCATAACCGAGTACACTCAATTTTGAAAATGAATATTTTTATCCATTTCTCAGTGAATATATACAGTTGAAGTCAGAATTATTAGCCCCCCTTTGACTTTTTTTTCTTTTTTAAATATTTCCTAAACGATGTTAAACAGAGCAAGGATATTTTCACAGTGTGTCTGATAATTTATTTTTCTGGAGAAAGTCTTATTTGTCTTCTTTTGGCTAGAATAAAAGCATTTATAAAAAACATTTTAGGGACAAAATTATTAGCCCCTTTAAGCTAATTTTTTTCGATAGTCTACAGAACAAACAATCGATTATACAATAACTTGCCTAATTACCCTAACTTGCCTAGTT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| gmdsrw685/rw685 (AB) | Homozygous | ♀+/- ♂+/- | Fig. 1  from Fowler et al., 2021 | ||
| gmdsrw685/+ (AB) | Heterozygous | ♀+/- ♂+/- | Fig. 1 from Fowler et al., 2021 | ||
| gmdsrw685/rw685; rw0Tg | Complex | 3 figures from Ohata et al., 2009 | 4 figures from Ohata et al., 2009 |
1 - 3 of 3
Show
Supplemental Information
- Genotyping protocol
- None
- Fowler, G., French, D., Rose, A., Squires, P., Anecito da Silva, C., Ohata, S., Okamoto, H., French, C.R. (2021) Protein fucosylation is required for Notch dependent vascular integrity in zebrafish. Developmental Biology. 480:62-68
- Ohata, S., Kinoshita, S., Aoki, R., Tanaka, H., Wada, H., Tsuruoka-Kinoshita, S., Tsuboi, T., Watabe, S., and Okamoto, H. (2009) Neuroepithelial cells require fucosylated glycans to guide the migration of vagus motor neuron progenitors in the developing zebrafish hindbrain. Development (Cambridge, England). 136(10):1653-1663
1 - 2 of 2
Show