Genomic Feature
fh49
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 1: 55248139 (GRCz11) (1) Details
- Nucleotide change
- A/T
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- T>A (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Leu>Stop at position 110 (1)
- Flanking Sequence
-
TAAAATCTGACATTTAAAAGGAGGACTAAACACACATTGTATTTACCAAATAAGCATGAAAGGGTTTGTTTTTGAGTGCGGTTGCGCCTGTAGCGAGCCTGCTGGCTTGTGTACAAGTTTGTTACCAAGTGAAAACACAACACCAGTGCACACAAAATAAAACACAGCAAACACACACATATACACACACACAAAAAAAGTGCAAAATCAAACAGTGAACGCACACATGCATGCAAACTCGCAATCCGCCGCGTATCAACCAAACAAACAATTAAAGAGTTAAAACTTAAACATTAAAACCTGCGGTAAAAAGTGTTTCTTCAAATCTACCGGAGCATCAATGTCCGCTTCACCATGTTGATTTGGCGTACACCGAGCAGTAGTTCTTGTCCACCATCGGGCAGAATCTCTTGGTGTGCGCTTTGGCCCCGGTGGCCCCACACAGGGGACACTTGTACTGTCGGAGATACGGGCACATCACGTCTCCATCGCGGTTTTTT
A/T AGTAGTGAGAGGTGTACACGGCCTCAGTCTCGCCGTTGTGTTTGCAGAAGCTGCAGAACTTTCTCTCTGCTGGGCTGCTCTTGGGTTTACCGCCCCCCGGGCTCGTGTTCTGCTCCGGTGAGTCGCGCGACCGAATCGGGCCGCTTGGAGACTCCAGCAGCGCGGCAGCCTGTTCGTCTGAATCCGCGTCAGATTGCATTTCTTGCCGCTTCATGCCTCTGATCATGTCCGCCAAACCCATGTAGTCCTTCCAAGGCTGAAAGTCCTGGTTTCTAGTCTCCATAGATCCATGAGCAGAAAGGATGAATTGGAGAAGAGAAAAAGCCATGTTGCTCTCCGAGCGCGCGATCAAAACAACTAGCACGCGCCGAGCACGCGTGCCTTTTAAAGGTCGCGTGCACGAGCCTGATTAATTAAAACGCGAAACTTGAAATGAGGGGAAATTGAGTGAGTTTCATTTTCAAAATGTCGTTTTAAACCCTGCTCTCAAGGTCACGAGA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| nanos3fh49/fh49 | Homozygous | ♀+/- ♂+/- | Fig. 6  from Beer et al., 2013 | Fig. 6 from Beer et al., 2013 | |
| nanos3fh49/fh49 (AB) | Homozygous | ♀+/- ♂+/- | Fig. 4 from Draper et al., 2007 | Fig. 4 from Draper et al., 2007 | |
| nanos3fh49/fh49 (AB) | Homozygous | ♀+/- ♂-/- | |||
| nanos3fh49/+ (AB) | Heterozygous | ♀+/+ ♂-/- | text only from Draper et al., 2007 | ||
| nanos3fh49/+ (AB) | Heterozygous | ♀-/- ♂+/+ | Fig. 3 from Draper et al., 2007 | Fig. 3 from Draper et al., 2007 | |
| nanos3fh49/fh49; uc1Tg | Complex |
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Supplemental Information
- Genotyping protocol
- None
- Beer, R.L., and Draper, B.W. (2013) nanos3 maintains germline stem cells and expression of the conserved germline stem cell gene nanos2 in the zebrafish ovary. Developmental Biology. 374(2):308-318
- Dranow, D.B., Tucker, R.P., and Draper, B.W. (2013) Germ cells are required to maintain a stable sexual phenotype in adult zebrafish. Developmental Biology. 376(1):43-50
- Draper, B.W., McCallum, C.M., and Moens, C.B. (2007) nanos1 is required to maintain oocyte production in adult zebrafish. Developmental Biology. 305(2):589-598
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