Genomic Feature
u11
- ID
- ZDB-ALT-060915-2
- Name
- u11
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- ENU
- Lab of Origin
- Steve Wilson Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 7: 30330444 (GRCz11) (1) Details
- Nucleotide change
- G/T
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- C>A (1)
- Transcript Consequence
- Missense (1)
- Protein Consequence
- Amino Acid Substitution: Thr>Lys at position 441 (1)
- Flanking Sequence
-
GAAAAATTATTGAGAAGTTATGAAGAGTTTACCAATTTAAATAAGAATCGACTCAGTTTTGATCAACAAGCCATATGTAATTAGTTTTTGTCCAAACTGCAGACAACTGTGCTTACTCTTTGCACACATGTGCTTAAATAAAAAAAAATGACAATCTGAAGTGAACAATAAGCTAATTGTTTAAAGAGCTGAACATGTGGTTTTGAAAAATAAAATTTATCAAGAAATGAGCCAAAGCAATTGAAAAAAACTGTAATGTAAAAATAAAACCACAATCATAGTATTTGTATTAATTTTTTTACACATTTAAAGTCTTTTGGTGACAAATGGTTGGAATCTAGTTTTTTGAAAGATATTGCCAATGATTTGGCTATCCATCTTTTTTGTGACTTTTGTGTAAGTTTTTGTCTTACCAGACGGTGCCGGCCTGCACTGCTGCAGAGATGGTCATGGCCTTGCTGATATCTCTGGTGAAGACGGCCGCTGCCAGACCGTATTCT
G/T TGTTGTTGGCTCTCTCAATCACTTCTTCAATTGTTTTGAACTTCATGATTTGCTGCACTGGCCCAAATATCTACAAAAAAAGTAGTTGTTTTAGTTAACCATTTGAATTTAGATTGATTATTTAGAGATGAAAAAAAATAAATCAGACCTCCTCCTTGGCGATGCGCATGTGGTCCTTCACATTAGAGAAAACTGTGGGCTCCACGAAGAAGCCTTTAGTAGGAGGAGCTTTGCCTCCACACTCCAGTTTGGCTCCTTCAGTGATGCCACTCTGGATGAGCTCCAGCACACGTCTCTGCTGCTCCTCGCTCACCTGACACAAACACACACACACACATTTGTCAATCATTATTAATGTACAGCTTTTCTTCAAATTCTGATAAAACTCCTACTTTGACTTAAACAAATATCAGTTGTTTTTAATATAATAGTTTAAAAAAGAATTGTAATATTTATGCACTGGATTTATTAGGCGTGTTTTAGTAAAATGTTAAAATTTG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| aldh1a2u11/u11 | Homozygous | Unknown | Fig. for (u11) from Phenotype Annotation (1994-2006) | ||
| aldh1a2u11/u11 | Homozygous | ♀+/- ♂+/- | 2 figures  from Grandel et al., 2002 | 5 figures from 2 publications |
1 - 2 of 2
Show
Supplemental Information
- Genotyping protocol
- None
- Grandel, H., and Brand, M. (2011) Zebrafish limb development is triggered by a retinoic acid signal during gastrulation. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(5):1116-1126
- Herrgen, L., Ares, S., Morelli, L.G., Schröter, C., Jülicher, F., and Oates, A.C. (2010) Intercellular Coupling Regulates the Period of the Segmentation Clock. Current biology : CB. 20(14):1244-1253
- Kazakova, N., Li, H., Mora, A., Jessen, K.R., Mirsky, R., Richardson, W.D., and Smith, H.K. (2006) A screen for mutations in zebrafish that affect myelin gene expression in Schwann cells and oligodendrocytes. Developmental Biology. 297(1):1-13
- Grandel, H., Lun, K., Rauch, G.J., Rhinn, M., Piotrowski, T., Houart, C., Sordino, P., Küchler, A.M., Schulte-Merker, S., Geisler, R., Holder, N., Wilson, S.W., and Brand, M. (2002) Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development (Cambridge, England). 129(12):2851-2865
1 - 4 of 4
Show