Genomic Feature
t24030
- ID
- ZDB-ALT-051123-14
- Name
- t24030
- Synonyms
-
- HE423FA (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Nüsslein-Volhard Lab
- Current Source
- European Zebrafish Resource Center (EZRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 21: 19681798 (GRCz11) (1) Details
- Nucleotide change
- A/G
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- A>G (1)
- Transcript Consequence
- Missense (1)
- Protein Consequence
- Amino Acid Substitution: Met>Val at position 170 (1)
- Flanking Sequence
-
ATATTCATATCGCAATATATATCGAAGCAAAACAAAATAACGCAATGTCTGATTTTTCCGATATCATGCAGCCCTACTTCACATAATATTAATAATAAAACACTATTTATTTTTTTATTTAATGAAATTATTTCTTACCTGAGAATAGATTAAGTAATACGGATGTGATGATGCCATGGCGTAAAAATGGCTGACACAGTTTCTCTTAAGACTGTTATTTTTTAAACTTCAAAATTGAATACAATGTATGTTATGCCATAATAAATTATAAAATAATAATTTTATACAAAATAATGACTTATTAAATTATAATATTGCTTTTTCTGGGAGTAGTGACAATAACATTATTAATAGTATTGAAACAGTATCTAAATCTGACTCATATATATGTCTTCTTTTTCCAGAGGGATTTCGGCATTGACTGCAAGCTGATAGAGAGGATAGAGGAGAACAGGTACAACACCTATGCCTCGGCAGAATGGATGAACAAGAAGAAGCAC
A/G TGTTCGTAGGTCTGAGCGCCAACGGGAGGCCGATGAGGGCCAAAAAGACCCGGAGAAAAAACACAGCCACACACTTTCTCCCCATTCCTATCGTGTAGCTACAACCCCACCAAAGGGAACATTTAACTGCACTGAGGAAAGACTTGGAATTTTTTTTCGTCAGTATAAATGGAACCATTTGGAGAAGAAGGCACTATGTAAAGAAACTACAAGAACTCATTATCACTGAGTCAAATCGTTGTTGCATATTTTGTTTAAGTTATTGGCACCAGGGAAAAAATATACTTTTTTAGTAAAGGAAAGGTTGGACACATGGACGAGAGGAATCGGACATTGCAACCTCCCAGAATGAACTGGAGAGACCTTTCACGGAGTGTATTGCTTGTGTGTATTTGTGTGTGTGACCTTTGGATGCAGTTATTTATGCTGTACTAACTCATACGAAACATTCTAACAGACTCTCAAGCTCTGTGACTCAGTGGACTGAAAGTTATGCAAAC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| fgf10at24030/t24030 | Homozygous | Unknown | Fig. for (t24030) from Phenotype Annotation (1994-2006) |
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Supplemental Information
- Genotyping protocol
- None
- Norton, W.H., Ledin, J., Grandel, H., and Neumann, C.J. (2005) HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development. Development (Cambridge, England). 132(22):4963-4973
- Habeck, H., Odenthal, J., Walderich, B., Maischein, H.-M., Tübingen 2000 screen consortium, and Schulte-Merker, S. (2002) Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Current biology : CB. 12(16):1405-1412
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