Genomic Feature
hi2137Tg
- ID
- ZDB-ALT-050809-2
- Name
- hi2137Tg
- Synonyms
-
- hi2137 (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- embryos treated with DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the plus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 21: 45717961 - 45717962 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Intron 1 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| ddx46hi2137Tg/hi2137Tg | Homozygous | Unknown | 4 figures from Hirabayashi et al., 2013 | 4 figures from Hirabayashi et al., 2013 | |
| ddx46hi2137Tg/hi2137Tg | Homozygous | ♀+/- ♂+/- | 4 figures  from Hozumi et al., 2012 | 6 figures from Hozumi et al., 2012 | |
| ddx46hi2137Tg/+ | Heterozygous | Unknown | 4 figures from Hirabayashi et al., 2013 | ||
| ddx46hi2137Tg/+ (AB) | Heterozygous | Unknown | |||
| ddx46hi2137Tg/+ (AB/TU) | Heterozygous | Unknown | |||
| ddx46hi2137Tg | Unknown | Unknown | Fig. for (hi2137) from Phenotype Annotation (1994-2006) | ||
| ddx46ha4/+; ddx46hi2137Tg/+ | Complex | 2 figures from Hozumi et al., 2012 | Fig. S7 from Hozumi et al., 2012 | ||
| ddx46hi2137Tg/hi2137Tg; zf603Tg | Complex | Fig. 6 from Hirabayashi et al., 2013 | Fig. 6 from Hirabayashi et al., 2013 | ||
| ddx46hi2137Tg/+; zf603Tg | Complex | Fig. 6 from Hirabayashi et al., 2013 |
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Supplemental Information
- Genotyping protocol
- None
- Hirabayashi, R., Hozumi, S., Higashijima, S.I., and Kikuchi, Y. (2013) Ddx46 Is Required for Multi-Lineage Differentiation of Hematopoietic Stem Cells in Zebrafish. Stem cells and development. 22(18):2532-42
- Hozumi, S., Hirabayashi, R., Yoshizawa, A., Ogata, M., Ishitani, T., Tsutsumi, M., Kuroiwa, A., Itoh, M., and Kikuchi, Y. (2012) DEAD-Box Protein Ddx46 Is Required for the Development of the Digestive Organs and Brain in Zebrafish. PLoS One. 7(3):e33675
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