Genomic Feature
p63cd
- ID
- ZDB-ALT-040224-8
- Name
- p63cd
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- unknown
- Protocol
- adult males treated with ENU
- Lab of Origin
- Mullins Laboratory
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
No data available
No data available
Variants
- Variant Type
- Unknown
- Variant Location
- Chr: 14 Details
- Nucleotide change
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- None
- Transcript Consequence
- None
- Protein Consequence
- Amino Acid Substitution: Val>Met at position 271 (1)
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| aurkbp63cd/p63cd (AB) | Homozygous | ♀+/- ♂+/- | Fig. 3  from Yabe et al., 2009 | ||
| aurkbp63cd/p63cd (AB) | Homozygous | ♀-/- ♂+/- | 4 figures from Yabe et al., 2009 | Fig. 9 from Yabe et al., 2009 | |
| aurkbp63cd/+ (AB) | Heterozygous | Unknown | |||
| aurkbp63cd/+ (AB/TU) | Heterozygous | Unknown | |||
| aurkbp63cd (AB/TU) | Unknown | Unknown | text only from Dosch et al., 2004 | ||
| aurkbhi1045Tg/+; aurkbp63cd/+ (AB) | Complex | Fig. 6 from Yabe et al., 2009 | |||
| lrmpt1497/t1497; aurkbp63cd/p63cd | Complex | Fig. 10 from Yabe et al., 2009 |
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Supplemental Information
- Genotyping protocol
- p63cd.pdf
- Nair, S., Lindeman, R.E., and Pelegri, F. (2013) In vitro oocyte culture-based manipulation of zebrafish maternal genes. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(1):44-52
- Yabe, T., Ge, X., Lindeman, R., Nair, S., Runke, G., Mullins, M.C., and Pelegri, F. (2009) The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryo. PLoS Genetics. 5(6):e1000518
- Dosch, R., Wagner, D.S., Mintzer, K.A., Runke, G., Wiemelt, A.P., and Mullins, M.C. (2004) Maternal Control of Vertebrate Development before the Midblastula Transition; Mutants from the Zebrafish I. Developmental Cell. 6(6):771-780
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