Genomic Feature
hi1780bTg
- ID
- ZDB-ALT-020426-8
- Name
- hi1780bTg
- Synonyms
-
- hi1780b (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the plus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 4: 8640616 - 8640617 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Exon 4 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| wnt5bhi1780bTg/hi1780bTg | Homozygous | Unknown | 4 figures  from 3 publications | ||
| wnt5bhi1780bTg/hi1780bTg | Homozygous | ♀+/- ♂+/- | Fig. 1 from Golling et al., 2002 | ||
| wnt5bhi1780bTg/hi1780bTg (AB/TU) | Homozygous | ♀+/- ♂+/- | 3 figures from Barresi et al., 2010 | Fig. 3 from Barresi et al., 2010 | |
| wnt5bhi1780bTg/+ (AB) | Heterozygous | Unknown | |||
| wnt5bhi1780bTg | Unknown | Unknown | Fig. for (hi1780b) from Phenotype Annotation (1994-2006) | ||
| wnt5bhi1780bTg (AB/TU) | Unknown | Unknown | |||
| wnt5bhi1780bTg/hi1780bTg + MO4-tp53 | Complex | 2 figures from Robu et al., 2007 |
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Supplemental Information
- Genotyping protocol
- hi1780btg.pdf
- Law, S.H., and Sargent, T.D. (2013) Maternal pak4 Expression is Required for Primitive Myelopoiesis in Zebrafish. Mechanisms of Development. 130(2-3):181-194
- Barresi, M.J., Burton, S., Dipietrantonio, K., Amsterdam, A., Hopkins, N., and Karlstrom, R.O. (2010) Essential genes for astroglial development and axon pathfinding during zebrafish embryogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(10):2603-2618
- Robu, M.E., Larson, J.D., Nasevicius, A., Beiraghi, S., Brenner, C., Farber, S.A., and Ekker, S.C. (2007) p53 activation by knockdown technologies. PLoS Genetics. 3(5):e78
- Kim, H.J., Schleiffarth, J.R., Jessurun, J., Sumanas, S., Petryk, A., Lin, S., and Ekker, S.C. (2005) Wnt5 signaling in vertebrate pancreas development. BMC Biology. 3:23
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
- Golling, G., Amsterdam, A., Sun, Z., Antonelli, M., Maldonado, E., Chen, W., Burgess, S., Haldi, M., Artzt, K., Farrington, S., Lin, S.Y., Nissen, R.M., and Hopkins, N. (2002) Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nature Genetics. 31(2):135-140
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