Genomic Feature
hi975Tg
- ID
- ZDB-ALT-020426-4
- Name
- hi975Tg
- Synonyms
-
- hi975 (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the minus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 21: 21012069 - 21012070 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Exon 2 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| ndr1hi975Tg/hi975Tg | Homozygous | ♀+/- ♂-/- | |||
| ndr1hi975Tg/hi975Tg | Homozygous | ♀+/- ♂+/- | 3 figures  from 3 publications | Fig. 4 from Pei et al., 2007 | |
| ndr1hi975Tg/hi975Tg | Homozygous | ♀-/- | Fig. 1 from Gore et al., 2007 | ||
| ndr1hi975Tg/hi975Tg | Homozygous | ♀-/- ♂-/- | 6 figures from Pei et al., 2009 | 2 figures from Pei et al., 2009 | |
| ndr1hi975Tg/hi975Tg | Homozygous | ♀-/- ♂+/+ | |||
| ndr1hi975Tg/+ (AB) | Heterozygous | Unknown | |||
| ndr1hi975Tg/+ (AB/TU) | Heterozygous | Unknown | |||
| ndr1hi975Tg | Unknown | Unknown | Fig. for (hi975) from Phenotype Annotation (1994-2006) | ||
| ndr1hi975Tg/hi975Tg + MO3-hsp90aa1.1 | Complex | Fig. 3 from Pei et al., 2009 | |||
| ndr1hi975Tg/hi975Tg + MO3-hsp90aa1.1 | Complex | Fig. 5 from Pei et al., 2007 |
1 - 10 of 13
Show
Supplemental Information
- Genotyping protocol
- hi975tg.pdf
- Lim, S., Kumari, P., Gilligan, P., Quach, H.N., Mathavan, S., and Sampath, K. (2012) Dorsal activity of maternal squint is mediated by a non-coding function of the RNA. Development (Cambridge, England). 139(16):2903-2915
- Hong, S.K., Jang, M.K., Brown, J.L., McBride, A.A., and Feldman, B. (2011) Embryonic mesoderm and endoderm induction requires the actions of non-embryonic Nodal-related ligands and Mxtx2. Development (Cambridge, England). 138(4):787-795
- Pei, W., and Feldman, B. (2009) Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia. Developmental Biology. 326(1):201-211
- Bennett, J.T., Stickney, H.L., Choi, W.Y., Ciruna, B., Talbot, W.S., and Schier, A.F. (2007) Maternal nodal and zebrafish embryogenesis. Nature. 450(7167):E1-E4
- Gore, A.V., Cheong, A., Gilligan, P.C., and Sampath, K. (2007) Gore et al. reply. Nature. 450(7167):E2-E4
- Pei, W., Noushmehr, H., Costa, J., Ouspenskaia, M.V., Elkahloun, A.G., and Feldman, B. (2007) An early requirement for maternal FoxH1 during zebrafish gastrulation. Developmental Biology. 310(1):10-22
- Pei, W., Williams, P.H., Clark, M.D., Stemple, D.L., and Feldman, B. (2007) Environmental and genetic modifiers of squint penetrance during zebrafish embryogenesis. Developmental Biology. 308(2):368-378
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
- Golling, G., Amsterdam, A., Sun, Z., Antonelli, M., Maldonado, E., Chen, W., Burgess, S., Haldi, M., Artzt, K., Farrington, S., Lin, S.Y., Nissen, R.M., and Hopkins, N. (2002) Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nature Genetics. 31(2):135-140
1 - 9 of 9
Show