Genomic Feature
tb237
- ID
- ZDB-ALT-001229-4
- Name
- tb237
- Synonyms
-
- AB37G (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- ENU
- Lab of Origin
- Nüsslein-Volhard Lab
- Current Source
-
Zebrafish International Resource Center (ZIRC)
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European Zebrafish Resource Center (EZRC) ( order this ) - Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 17: 38589068 (GRCz11) (1) Details
- Nucleotide change
- C/T
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- None
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
ATGGGTAATATGCAGACTCGAGTTGATAACGTTAATAAAGCAGCCAAGCAACTTGAAGACAGCAGACATCCACAAACAAAACAAGTGAAAGACTGTCAAATTCGTCTCAATAAGAGGTAAGATTTAAACAGTATTCCTAAATGTAAATATATAAAATATTTATGAATGATCTGCAATGTTACTTTTTCTATTCTCACAGATGGGAGGCTTTTAAAGCAATGGTCGAAGATAAGAAACATAGGGTAGATTCTGCTCTTAGCCTACATAACTATGATCTTGATTGTGATGAGACAGAATCATGGATAAAAGAAAAGACGAGAGTCATTGAGTCTACACAGGATCTTGGGAATGACCTTGCTGCTGTCATTACTATTCAAAGGAAGCTTTTTGGCATGGAAAGAGACCTTGCTGCCATCCAAGATAAGTTGGATTCCCTGCGTGACGAGGCCCAGAAGCTTGTAAAGGAGCACCCAGAAAATGCTTCTGATATACTTGCCAGA
C/T AGGAAGAGTTGGATGCAGCATGGGACACCTTGAAACGTACCCTGAAAGACCGTGAAGACTCTCTTGGGGAGGTCAGCAAGCTGCAGACCTTCTTACAGGACATGGACGATTTTCAAGCTTGGTTGTTCAAGTCACAGAAGGCTGTTGCTTCTGAAGATATGCCAGATGGTTTACCAGAGGCTGAGCAACTCCTGAATCTCCATGATGCTTTGAGGCATGATATGGATGGCCATGAGGAAGACTACCATCGTGTGAAAGACACAGGAGCTGCTGTTATTCAAGGTCAAGAAGATGATCCTCAGTACCAGCAACTGGAACAGAGGCTGGAGGGTCTTGATAAGGGCTGGGGTGAGCTTCACAAAATGTGGGACAGTCGCAAGAACTTCCTAGATCAGGGTCTCGGTTTCCAACAATTCATGAGAGATGCCAAACAGGCTGATGCCATCTTAAATAATCAGGTATATATGCAGAGACTTTTTCATTTATTGAATCAAAATAGA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| sptbtb237/tb237 | Homozygous | Unknown | 4 figures  from 3 publications | 2 figures from Liao et al., 2000 | |
| sptbtb237/tb237 | Homozygous | ♀+/- ♂+/- | |||
| sptbtb237/+ (AB) | Heterozygous | Unknown |
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Supplemental Information
- Genotyping protocol
- tb237.pdf
- Liao, E.C., Paw, B.H., Peters, L.L., Zapata, A., Pratt, S.J., Do, C.P., Lieschke, G., and Zon, L.I. (2000) Hereditary spherocytosis in zebrafish riesling illustrates evolution of erythroid ß-spectrin structure, and function in red cell morphogenesis and membrane stability. Development (Cambridge, England). 127(23):5123-5132
- Oates, A.C., Brownlie, A., Pratt, S.J., Irvine, D.V., Liao, E.C., Paw, B.H., Dorian, K.J., Johnson, S.L., Postlethwait, J.H., Zon, L.I., and Wilks, A.F. (1999) Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expresssion patterns: only jak2a is expressed during erythropoiesis. Blood. 94(8):2622-2636
- Haffter, P., Granato, M., Brand, M., Mullins, M.C., Hammerschmidt, M., Kane, D.A., Odenthal, J., van Eeden, F.J., Jiang, Y.J., Heisenberg, C.P., Kelsh, R.N., Furutani-Seiki, M., Vogelsang, E., Beuchle, D., Schach, U., Fabian, C., and Nüsslein-Volhard, C. (1996) The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development (Cambridge, England). 123:1-36
- Ransom, D.G., Haffter, P., Odenthal, J., Brownlie, A., Vogelsang, E., Kelsh, R.N., Brand, M., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Mullins, M.C., and Nüsslein-Volhard, C. (1996) Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development (Cambridge, England). 123:311-319
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