ZFIN ID: ZDB-LAB-110328-2
Vergunst Lab
PI/Director: Vergunst, Annette
Contact Person: Vergunst, Annette
Email: annette.vergunst@umontpellier.fr
URL: http://www.umontpellier.fr/recherche/unites-de-recherche/virulence-bacteriennes-et-maladies-infectieuse/
Address: INSERM U1047 / University of Montpellier 1 UFR Medecine Site de Nimes 186, Chemin du Carreau de Lanes 30908 Nimes
Country: France
Phone: +33 4 66 02 81 57
Fax:
Line Designation: None assigned


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Gigan, Johan Graduate Student Boyer, Julien Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Hagege, A., Saada-Bouzid, E., Ambrosetti, D., Rastoin, O., Boyer, J., He, X., Rousset, J., Montemagno, C., Doyen, J., Pedeutour, F., Parola, J., Bourget, I., Luciano, F., Bozec, A., Cao, Y., Pagès, G., Dufies, M. (2022) Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma. Cell reports. Medicine. 3:100659
Hagege, A., Ambrosetti, D., Boyer, J., Bozec, A., Doyen, J., Chamorey, E., He, X., Bourget, I., Rousset, J., Saada, E., Rastoin, O., Parola, J., Luciano, F., Cao, Y., Pagès, G., Dufies, M. (2021) The Polo-like kinase 1 inhibitor onvansertib represents a relevant treatment for head and neck squamous cell carcinoma resistant to cisplatin and radiotherapy. Theranostics. 11:9571-9586
Chudinova, A.V., Rossel, M., Vergunst, A., Le-Masson, G., Camu, W., Raoul, C., Lumbroso, S., Mouzat, K. (2019) Theme 4 In vivo experimental models. Amyotrophic lateral sclerosis & frontotemporal degeneration. 20:160-187
Gomes, M.C., Tasrini, Y., Subramoni, S., Agnoli, K., Feliciano, J.R., Eberl, L., Sokol, P., O'Callaghan, D., Vergunst, A.C. (2018) The afc antifungal activity cluster, which is under tight regulatory control of ShvR, is essential for transition from intracellular persistence of Burkholderia cenocepacia to acute pro-inflammatory infection. PLoS pathogens. 14:e1007473
Carnell, S.C., Perry, J.D., Borthwick, L., Vollmer, D., Biboy, J., Facchini, M., Bragonzi, A., Silipo, A., Vergunst, A.C., Vollmer, W., Khan, A.C.M., De Soyza, A. (2018) Targeting the Bacterial Cytoskeleton of the Burkholderia cepacia Complex for Antimicrobial Development: A Cautionary Tale.. International Journal of Molecular Sciences. 19(6)
Vergunst, A.C., Carranza, N.L., Zhang, L., Gomes, M.C., Tasrini, Y., Meijer, A.H., O'Callaghan, D. (2017) Macrophages as drivers of an opportunistic infection. Microbial cell (Graz, Austria). 4:362-364
Mesureur, J., Feliciano, J.R., Wagner, N., Gomes, M.C., Zhang, L., Blanco-Gonzalez, M., van der Vaart, M., O'Callaghan, D., Meijer, A.H., Vergunst, A.C. (2017) Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation. PLoS pathogens. 13:e1006437
Agnoli, K., Frauenknecht, C., Freitag, R., Schwager, S., Jenul, C., Vergunst, A., Carlier, A., and Eberl, L. (2014) The Third Replicon of Members of the Burkholderia cepacia Complex, Plasmid pC3, Plays a Role in Stress Tolerance. Applied and environmental microbiology. 80(4):1340-1348
Mesureur, J., Vergunst, A.C. (2014) Zebrafish embryos as a model to study bacterial virulence. Methods in molecular biology (Clifton, N.J.). 1197:41-66
Agnoli, K., Schwager, S., Uehlinger, S., Vergunst, A., Viteri, D.F., Nguyen, D.T., Sokol, P.A., Carlier, A., and Eberl, L. (2012) Exposing the third chromosome of Burkholderia cepacia complex strains as a virulence plasmid. Molecular Microbiology. 83(2):362-78
Lavigne, J.P., Vergunst, A.C., Goret, L., Sotto, A., Combescure, C., Blanco, J., O'Callaghan, D., and Nicolas-Chanoine, M.H. (2012) Virulence Potential and Genomic Mapping of the Worldwide Clone Escherichia coli ST131. PLoS One. 7(3):e34294
Vergunst, A.C., Meijer, A.H., Renshaw, S.A., and O'Callaghan, D. (2010) Burkholderia cenocepacia creates an intra-macrophage replication niche in zebrafish embryos, followed by bacterial dissemination and establishment of systemic infection. Infection and Immunity. 78(4):1495-1508
O'Callaghan, D., and Vergunst, A. (2010) Non-mammalian animal models to study infectious disease: worms or fly fishing?. Current opinion in microbiology. 13(1):79-85