Molecular weight profile and surface morphology of the polysaccharides from fruiting bodies of Cordyceps militaris under different drying treatments. (A) Molecular weight profiles of CMFPs. (B) SEM photomicrographs of CMFPs. (H) CMFP-H. (I) CMFP-I. (F) CMFP-F.

Elution curve of DEAE-52 and Sephacryl S-400 for CMFPs. (A) Elution curve of DEAE-52 of CMFPs. (B) Elution curve of Sephacryl S-400 of CMFPs. (H) CMFP-H. (I) CMFP-I. (F) CMFP-F. (H₀) CMFP-H₀. (I₀) CMFP-I₀. (F₀) CMFP-F₀. (H₁) CMFP-H₁. (I₁) CMFP-I₁. (F₁) CMFP-F₁.

Effect of CMFPs on the histopathological structure (HE staining) of intestinal in inflammatory bowel disease zebrafish. (A) 5 h. (B) 3 d. (C) 6 d. (a) NC group. (b) MC group. (c) CMFP-H group. (d) CMFP-I group. (e) CMFP-F group. (f) PC group.

Effects of CMFPs on the activities of antioxidant enzymes and immune-related enzymes in the intestine of zebrafish with inflammatory bowel disease at 5 h, 3 d, and 6 d. (A) The ROS levels, SOD and CAT activities, and MDA content. (B) The ACP, AKP, LZM, and MPO activities. MC compared with NC, **p < 0.01, *p < 0.05; CMFPs and PC groups compared with MC indicated significant differences between groups marked with different letters (p < 0.05).

Effect of CMFPs on the expressions of inflammatory cytokines and MyD88/NF-κB Signaling Pathways in the intestine of zebrafish with inflammatory bowel disease at 5 h, 3 d, and 6 d. MC compared with NC, **p < 0.01, *p < 0.05; CMFPs and PC groups compared with MC indicated significant differences between groups marked with different letters (p < 0.05).