- Title
-
Effects of Aroclor 1254 on Intestinal Immunity, Metabolism, and Microflora in Zebrafish
- Authors
- Zhu, D.H., Nie, F.H., Zhang, M., Wei, W., Song, Q.L., Hu, Y., Kang, D.J., Chen, Z.B., Lin, H.Y., Chen, J.J.
- Source
- Full text @ Front Nutr
Intestinal tissue sections at different doses [(A1,2) Control, (B1,2) L-PCBs, (C1,2) M-PCBs, (D1,2) H-PCBs, 2.4.: Neutropenia, 1.6.8 intestinal villus injury, 3.7.5 epithelial injury, HE, 200X 400X]. |
Change map [(A). CAT (B).SOD (C). MDA (D). ROS (E).GSH (F). T-AOC (G). DAO (H). D-LA, *P < 0.05, **P < 0.01 compared to control group]. |
Changes of cytokines (TNF-α?IL-1β?IL-6 and IL-8) mRNA expression in zebrafish exposure to [(A). TNF-α (B). IL-1β (C). IL-6 (D).IL-8, *P < 0.05, **P < 0.01 compared to control group]. |
Change map of the intestinal metabolic group [(A). Metabolite changes (B). Venn diagram of metabolites in each experimental group (C). PLS-DA diagram of metabolites in each experimental group (D). Hierarchical clustering heat map, *P < 0.05, **P < 0.01, ***P < 0.001]. |
Analysis of intestinal microorganisms of zebrafish treated with different doses of PCBs [(A). The microbial composition of each dose group (B). The difference in composition of each dose group was analyzed by (C). PCA analysis (D). PLS-DA analysis (E). The difference in genus level between the control group and the experimental group]. |
Platts analysis. |