FIGURE 1

Effect of betaine on the mRNA expression of Wnt10b, GSK-3β, and β-catenin in the liver of zebrafish. (A) The mRNA expression of Wnt10b; (B) The mRNA expression of GSK-3β; (C) The mRNA expression of β-catenin. Values are expressed as means ± sem (n = 3). Statistically significant differences are denoted by different letters (p < 0.05).
FIGURE 2

Effect of betaine on the mRNA expression of CAT, SOD, and GSH-PX in the liver of zebrafish. (A) The mRNA expression of CAT; (B) The mRNA expression of SOD; (C) The mRNA expression of GSH-PX. Values are expressed as means ± sem (n = 3). Statistically significant differences are denoted by different letters (p < 0.05).
FIGURE 3

Effect of betaine on the level of ROS in the liver of zebrafish. (A) The level of O2·−; (B) The level of ·OH; (C) The level of H2O2. Values are expressed as means ± sem (n = 3). Statistically significant differences are denoted by different letters (p < 0.05).
FIGURE 4

Effect of betaine on the activities of antioxidant enzymes in the liver of zebrafish. (A) The activity of CAT; (B) The activity of SOD; (C) The activity of GSH-PX. Values are expressed as means ± sem (n = 3). Statistically significant differences are denoted by different letters (p < 0.05).
FIGURE 5

The mechanism by which betaine regulates the production of ROS through Wnt10b/β-catenin signaling pathway in the zebrafish liver.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Physiol.
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.