FIGURE SUMMARY
Title

Dendrobium catenatum Lindl. Water Extracts Attenuate Atherosclerosis

Authors
Han, J., Dong, J., Zhang, R., Zhang, X., Chen, M., Fan, X., Li, M., Li, J., Zhu, J., Shang, J., Yue, Y.
Source
Full text @ Mediators Inflamm.
Figure 1

HPLC profile of DHWE.

Figure 2

DHWE reduced the AS in AS zebrafish. (a) HE staining results showed that DHWE reduce vascular stenosis in AS zebrafish. (b) EVG staining results showed that DHWE reduced the fibrosis of plaques in AS zebrafish blood vessels. (c) Oil red O staining results showed that DHWE reduced the lipids in the plaques in the blood vessels of AS zebrafish.

Figure 3

DHWE reduced the early AS in AS zebrafish. (a) DHWE reduced cholesterol accumulation in AS zebrafish blood vessels. (b) DHWE reduced macrophage infiltration in AS zebrafish blood vessels.

Figure 4

DHWE reduced lipid accumulation in AS zebrafish. (a) The results of Nile red staining showed that DHWE reduced the blood lipid level in AS zebrafish. DHWE reduced the (b) TC content and (c) TG content in AS zebrafish. # and ## compared to the control group and and compared to the AS group.
Figure 5

DHWE reduced oxidative stress in AS zebrafish. (a) The results of DCFH-DA assay showed that DHWE reduced the ROS activity in AS zebrafish. (b) DHWE reduced MDA content in AS zebrafish. (c) DHWE increased SOD activity in AS zebrafish. # and ## compared to the control group and and compared to the AS group.
Figure 6

DHWE reduced the number of neutrophils in AS zebrafish.

Figure 7

DHWE improved LSS-induced EC dysfunction. (a) DHWE increased the LSS-induced decrease in NO release from EA.hy926 cells. (b) DHWE decreased the LSS-induced increase in ET-1 release from EA.hy926 cells. (c) DHWE increased the LSS-induced decrease in PGI2 release from EA.hy926 cells. (d) DHWE increased the LSS-induced decrease of the eNOS mRNA level. (e) DHWE decreased the LSS-induced increase of the ET-1 mRNA level. (f) DHWE increased the LSS-induced decrease of the PGIS mRNA level. (g) The results of the DAF-FM DA assay showed that DHWE increase the LSS-induced decrease in NO activity in EA.hy926 cells. ## compared to ; and compared to .
Figure 8

DHWE alleviated LSS-induced oxidative stress. (a) The results of the DCFH-DA assay showed that DHWE attenuate the LSS-induced increase in ROS activity in EA.hy926 cells. (b) DHWE increased the LSS-induced decrease in SOD activity in EA.hy926 cells. (c) DHWE decreased the LSS-induced increase in MDA content in EA.hy926 cells. (d) DHWE increased the LSS-induced decrease in GSH content in EA.hy926 cells. (e) DHWE decreased the LSS-induced increase in GSSG content in EA.hy926 cells. ## compared to ; and compared to .
Figure 9

DHWE improved LSS-induced inflammation. DHWE decreased the LSS-induced increase in (a) ICAM-1 and (b) VCAM-1 mRNA levels. ##p < 0.01 compared to 0 min LSS + 0 μg/mL DHWE; ∗∗p < 0.01 compared to 30 min LSS + 0 μg/mL DHWE.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mediators Inflamm.
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