FIGURE SUMMARY
Title

Polystyrene Nanoplastics Can Alter the Toxicological Effects of Simvastatin on Danio rerio

Authors
Barreto, A., Santos, J., Amorim, M.J.B., Maria, V.L.
Source
Full text @ Toxics

Effects of functionalized polystyrene nanoplastics on malformations appearance (A), heartbeat (B), hatching (C) and mortality (D) on zebrafish (Danio rerio) embryos/larvae exposed for 96 h. Results are expressed in average value (AV) ± standard error (SE).

Effects of simvastatin on malformations appearance (A), heartbeat (B), hatching (C) and mortality (D) on zebrafish (Danio rerio) embryos/larvae exposed for 96 h. Results are expressed in average value (AV) ± standard error (SE). * Significant differences to control (p < 0.05).

Malformations detected in the organisms after the exposure to 15 µg/L of simvastatin, from 48 up to 96 h exposure: (A) Pericardial edema; (B) Yolk sac edema; (C) Tail malformation; (D) Delayed hatching at 96 h of exposure; (E) Normal larvae.

Effects of combined exposure of functionalized nanoplastics (NPls) with simvastatin (SIM) on malformations appearance (A), heartbeat (B), hatching (C) and mortality (D) on zebrafish (Danio rerio) embryos/larvae exposed for 96 h. Results are expressed in average value (AV) ± standard error (SE). * Significant differences to control (p < 0.05).

Malformations detected in the organisms after the exposure to combined exposures of nanoplastics (0.015 mg/L) and simvastatin (12.5 or 15 µg/L), from 48 up to 96 h exposure. (A) Pericardial edema; (B) Yolk sac edema; (C) Tail malformation; (D) Delayed hatching at 72 h of exposure detected on the combination 0.015 mg/L NPls + 15 µg/L SIM; (E) Normal larvae.

Acknowledgments
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