ZFIN All Figures, Tran <i>et al.</i>, 2021

Tran et al., 2021

ZDB-PUB-210113-1
PMID:33430197
Figure 1
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Figure 4

FIGURE SUMMARY

Title: Comparative Analysis of Neurotoxicity of Six Phthalates in Zebrafish Embryos
Authors: Tran, C.M., Do, T.N., Kim, K.T.
Source: Full text @ Toxics

Figure 1

Locomotor responses of larval zebrafish (n = 48) upon exposure to diisononyl phthalate (BBzP) (A,B), di-2-ethylhexyl phthalate (DEHP) (C,D), and benzyl butyl phthalate (DiNP) (E,F). Locomotor response was divided into the dark (A,C,E) and light phase (B,D,F) for each phthalate. (↑) represents a significant hyperactivity compared with control and (↓) indicates a significant hypoactivity compared with control. (* p < 0.05; ** p < 0.01). Dist: distance. Dur: duration. The attention is needed on different scale of total distance in each graph.

Figure 2

FIs of Tg(huc:EGFP), Tg(sox10:EGFP), and Tg(mbp:GFP) for BBzP (A), DEHP (B), and DiNP (C). FI was averaged from 10 images/treatment. Values are expressed as the mean ± SEM. * p < 0.05.

Figure 3

Representative images of Tg(HuC:EGFP), Tg(sox10:EGFP), and Tg(mbp:GFP) in untreated controls and embryos treated with BBzP, DEHP, and DiNP at 10 K μg/L.

Figure 4

Fold change to expression levels of ache, dat, drd1b, and th in zebrafish larvae exposed to BBzP (A), DEHP (B), and DiNP (C) at concentrations of 5, 50, and 500 μg/L. Values are expressed as the mean ± SEM. * p < 0.05.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Toxics

Tran et al., 2021 ZDB-PUB-210113-1 PMID:33430197

Comparative Analysis of Neurotoxicity of Six Phthalates in Zebrafish Embryos

Tran et al., 2021

ZDB-PUB-210113-1
PMID:33430197