Figure 1

Carbamazepine (CBZ) effects on the development of zebrafish larvae after 6 d exposure (mean ± SEM). (A) Early spontaneous movement rate at 28–29 hpf (n = 16); (B) Hatching rate at 48–62 hpf (n = 50); (C) Heart rate at 72 hpf (n = 12); (D) Body length at 96 hpf (n = 10). Bars with different letters indicate significant differences between each other (p < 0.05).
Figure 2

The steady state mRNA levels of (A) gabra1, (B) grin1b, (C) gria2b, (D) abat, (E) gad1b in zebrafish larvae following exposure to CBZ for 6 d (mean ± SEM). Bars with different letters indicate significant differences between each other (n = 5; p < 0.05).
Figure 3

The acetylcholine (AchE) activity, gamma-aminobutyric acid (GABA) and glutamate (Glu) concentrations in the zebrafish larvae after 6 d of exposure to CBZ (mean ± SEM). (A) Acetylcholine activity; (B) Gamma-aminobutyric acid concentration; (C) Glutamate concentration. Bars with different letters indicate significant differences among groups (n = 3; p < 0.05).
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Environ. Res. Public Health
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.