FIGURE SUMMARY
Title

Inhibition of macrophage migration in zebrafish larvae demonstrates in vivo efficacy of human CCR2 inhibitors

Authors
Sommer, F., Ortiz Zacarı As, N.V., Heitman, L.H., Meijer, A.H.
Source
Full text @ Dev. Comp. Immunol.
Fig. 1

Fig. 1. The Ccl2/Ccr2 and Cxcl11aa/Cxcr3.2 chemokine axes contribute to inflammation in zebrafish larvae.

Fig. 2

Fig. 2. Locally injected human CCL2 and CXCL11 proteins attract macrophages to the hindbrain ventricle of zebrafish larvae.

Fig. 3

Fig. 3. The human CCR2 inhibitor CCR2-RA-[R] inhibits macrophage recruitment in zebrafish larvae.

Fig. 4

Fig. 4. Zebrafish larvae are a powerful screening platform for CCR2 inhibitors.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Comp. Immunol.
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