FIGURE SUMMARY
Title

Chronic Microcystin-LR Exposure Induces Abnormal Lipid Metabolism via Endoplasmic Reticulum Stress in Male Zebrafish

Authors
Zhang, D., Lin, W., Liu, Y., Guo, H., Wang, L., Yang, L., Li, L., Li, D., Tang, R.
Source
Full text @ Toxins (Basel)

Microcystin-LR (MC-LR) influences on hepatic lipid accumulation in adult male zebrafish exposed to low levels of MC-LR (0, 1, 5, and 25 µg/L) for 60 days. (A) Liver histology (hematoxylin/eosin (H&E) stain) and (B) histochemistry (Oil Red O stain). Arrows indicate hepatic steatosis. Lipid droplets are red-colored and nuclei are blue-colored with Oil Red O stain. (C,D) The relative areas for liver vacuoles in H&E stain and lipid droplets in Oil Red O stain were analyzed by Image-Pro plus 6.0. Values are reported as mean ± standard error (SE) (n = 5) and normalized to percentage of field area. Significant differences at p < 0.05 are indicated by different letters above bars.

Acknowledgments
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